To examine the impact of homozygous genetic disruption of insulin receptor substrate (IRS)-1 (IRS-1(-/-)) or IRS-2 (IRS-2(-/-)) on basal and insulin-stimulated carbohydrate and lipid metabolism in vivo, we infused 18-h fasted mice (wild-type (WT), IRS-1(-/-), and IRS-2(-/-)) with [3-(3)H]glucose and [(2)H(5)]glycerol and assessed rates of glucose and glycerol turnover under basal (0-90 min) and...

To examine the impact of homozygous genetic disruption of IRS-1 (IRS-1-/-) or IRS-2 (IRS-2-/-) on basal and insulin stimulated carbohydrate and lipid metabolism in vivo we infused 18-h fasted mice (WT, IRS1-/and IRS2-/-) with [3-3H]glucose and [H5]glycerol and assessed rates of glucose and glycerol turnover under basal (0-90 min) and hyperinsulinemic-euglycemic clamp (90-210 min; 5 mM glucose a...

Green networking techniques usually shut down the least utilized links and/or routers during off-peaks hours. In a prior work, we showed conclusively that these actions trigger what is known as hot-potato routing changes. These changes are well known to negatively impact the operation of the Border Gateway Protocol (BGP). Critically, they may cause packet loss due to slow BGP convergence and in...

We and others recently generated mice with a targeted disruption of the insulin receptor substrate 1 (IRS-1) gene and demonstrated that they exhibited growth retardation and had resistance to the glucose-lowering effect of insulin. Insulin initiates its biological effects by activating at least two major signalling pathways, one involving phosphatidylinositol 3-kinase (PI3-kinase) and the other...

Intelligent reflecting surface (IRS) is a promising technology to enhance the coverage and performance of wireless networks. We consider application IRS non-orthogonal multiple access (NOMA), where base station transmits superposed signals users by virtue an IRS. The IRS-assisted NOMA networks with imperfect successive interference cancellation (ipSIC) perfect (pSIC) investigated invoking 1-bit...

In this paper we describe our ongoing work in developing a choreography for IRS-III. IRS-III is a framework and platform for developing WSMO based semantic web services. Our choreography framework is based on the KADS system-user co-operation model and distinguishes between the direction of messages within a conversation and which actor has the initiative. The implementation of the framework is...

In this paper we describe our ongoing work in developing a choreography for IRS-III. IRS-III is a framework and platform for developing WSMO based semantic web services. Our choreography framework is based on the KADS system-user co-operation model and distinguishes between the direction of messages within a conversation and which actor has the initiative. The implementation of the framework is...

estimation of vegetation cover attributes, such as the leaf area index (lai), is an important step in identifying the amount of water use for some plants. the goal of this study is to investigate the feasibility of using irs liss-iii data to retrieve lai. to get a lai retrieval model based on reflectance and vegetation index, detailed field data were collected in the study area of eastern iran....

The low-mass star formation region associated with the reflection nebula Cederblad 110 in the Chamaeleon I cloud was mapped with the Australian Telescope Compact Array (ATCA) at 6 and 3.5 cm. Altogether 11 sources were detected, three of which are previously known low mass young stellar objects associated with the nebula: the illuminating star IRS 2 (Class III, Einstein X-ray source CHX 7), the...