Submit Manuscript | http://medcraveonline.com Abbreviations: ANO: Anorexia; BCM: Body Cell Mass; BIA: Bioelectrical Impedance Analysis; BMI: Body Mass Index; BW: Body Weight; BWC: Body Weight Loss And Composition; COX: Cyclo Oxygenase; DXA: Dual-Energy X-Ray Absorptiometry; FFM: Fat-Free Mass; FM: Fat Mass; GH: Growth Hormone; HAQ: Health Assessment Score; IGF: Insulin-Like Growth Factor; IL-1ß...

BACKGROUND Spinal cord injury stimulates an inflammatory reaction that causes substantial secondary damage inside the injured spinal tissue. The purpose of this study was to determine the anti-inflammatory effect of oleuropein on traumatized spinal cord. METHODS Rats were randomly divided into four groups of 7 rats each as follows: Sham-operated group, trauma group, and oleuropein treatment g...

Introduction: Gliomas are the most prevalent type of primary intracranial tumors, representing 80% all brain neoplasms.In Sudan Brain tumors have been as leading cause mortality among children and thirdcausative death young adults.World Health Organization (WHO) classification2021, categorized gliomas into lower-grades (LGG,grades II III) andglioblastoma (GBM, grade IV).Gliomas surrounded by po...

Background . Today we have active development of ophthalmic surgery, but the role cytokines in pathogenesis bullous keratopathy cornea remains insufficiently studied at present. The aim To study dynamics local cytokine profile by using personalized treatment with suspension autologous blood mononuclears. Material and methods Two groups patients were formed: main group (30 people, 30 eyes), who ...

Introduction: Pandemic Influenza A (H1N1)v pneumonia has led to a notable increase of admissions to intensive care units. A cytokinemediated inflammatory response has been well documented in pneumonia and acute respiratory distress syndrome. However, few studies have focused on the role of these inflammatory mediators in infections caused by the Influenza A (H1N1)v. In this study, we assess the...

Background: Cannabinoids (CBs) have been found to regulate the immune system, affect innate and adaptive immune responses, and reduce inflammatory reactions. This study assessed the therapeutic effects of GW-405833 synthetic CB2 agonist on inflammatory factors as well as locomotor activity in experimental autoimmune encephalomyelitis (EAE). Methods: In this experimental study, 48 adult male ...

The study aimed to investigate the effects of oral Lactobacillus plantarum (Lp) administration on some serum/tissue (uterus) antioxidant and cytokine levels as well histopathologic changes in female rats exposed chronically Cd. For this purpose, were separated into four groups including control (C, n = 8), cadmium (Cd, Lp (n Cd + 8). (dissolved water at a dose 2.04 mg/mL) was orally administere...

Alterations in microRNA (miRNA) expression may contribute to COPD pathogenesis. In COPD, lung fibroblast repair functions are altered in multiple ways, including extracellular mediator release. Our prior study revealed miR-503 expression is decreased in COPD lung fibroblasts, although the exact role played by miR-503 is undetermined. The current study examined a role of miR-503 in cytokine, gro...

BACKGROUND The aim of the present study was to evaluate the effects of glucosamine-chondroitin sulphate combination on internal derangements of temporomandibular joint in clinical and biochemical manners. MATERIAL AND METHODS This randomized clinical study included 31 cases reporting joint tenderness, in which disc displacement was detected on MR imaging. In all patients, synovial fluid sampl...

BACKGROUND Platelet-rich plasma therapies for tendinopathy appear to provide moderate pain reduction. However, the biological mechanisms behind the observed clinical effects remain poorly characterized. QUESTIONS/PURPOSES The purpose of this study was to explore whether platelet-rich plasma modifies the inflammatory/angiogenic status of already inflamed tenocytes by examining (1) gene express...