several studies have focused on polymorphisms of major histocompatibility complex (mhc) in sheep, ovar-mhc. this molecule plays a pivotal role in antigen presentation for eliciting immune responses against invading pathogens. the best-characterized genetic control of disease resistance and immune response in animals is associated with mhc. numerous molecular genetic investigations have been und...

The elimination of a foreign antigen is a function of the antibody, complement and phagocyte systems. When an immune complex is formed in the circulation, clearance is effected by cells of the reticuloendothelial system. Macrophages and polymorphonuclear cells have both IgG Fc and C3b complement receptors so that opsonisation by either the classical or the alternative pathway of complement acti...

Inflammatory rheumatic diseases are characterized by inflammation resulting from the immune dysregulation that usually attacks joints, skin and internal organs. Many of them are considered as complex disease that may be predisposed by multiple genes and/or genetic loci, and triggered by environmental factors such as microbiome and cellular stress. The major histocompatibility complex class I ch...

General Introduction Immunogenetics: host genetics and the immune system Candidate gene approach Genetic variation of the immune system and its mediators Chlamydia trachomatis infections of the urogenital tract Inflammatory Bowel Diseases Arthralgia and spondyloarthropathy Thromboembolism Immunomodulatory aspects of probiotics The immune response and genetic predisposition have been implicated ...

The following review is based on notes used in the teaching of clinical immunology to veterinary students. Immune diseases of the dog are placed into six different categories: (1) type I or allergic conditions; (2) type II or auto- and allo-antibody diseases; (3) type III or immune complex disorders; (4) type IV or cell-mediated immune diseases; (5) type V conditions or gammopathies; and (6) ty...

background and aims. melatonin is a circulating hormone that is mainly released from the pineal gland. it possesses antioxidant, free-radical scavenging, and immune-enhancing properties. a growing number of studies reveal a complex role for melatonin in influencing various diseases, including diabetes and periodontal diseases. the aim of this study was to examine the possible links between sali...