This study aimed to highlight and focus on curcumin’s role in enhancing the body defense mechanism against tuberculosis (TB) infection, using a narrative review. review was identified by four search engines: PubMed, Science Direct, Research Gate, Google Scholar. We found that as an immunomodulator, curcumin reduces production of specific cytokines inhibiting transcription factor. In same mechan...

Persistent and excessive stress of modern life has made us recognize with new class of disease called stress-related diseases. In Ayurveda, rasayanas have been mentioned as a set of rejuvenating measures aimed towards youthful rich life free of diseases. It promotes longevity via optimizing cellular level nourishment (Svasthasya orjaskaram). The term rasayana means transportation of nutritional...

Background Although immunomodulators are increasingly used in Crohn's disease (CD), a significant number of gastroenterologists still use 5-aminosalicylate (5-ASA) in combination with azathioprine (AZA) or 6-mercaptopurine (6-MP); there is limited evidence regarding the benefit of concomitant 5-ASA with AZA/6-MP compared with AZA/6-MP monotherapy for the treatment of CD. Study Design A total ...

Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important immunomodulator during the development of joint inflammation.

back ground: candida albicans is a member of the normal human microflora. c. albicans cell wall is composed of several protein and carbohydrate components which have been shown to play a crucial role in c. albicans interaction with the host immune system. major components of c. albican cell wall are carbohydrates such as mannans, β glucans and chitins, and proteins that partially modulate the h...

We have previously observed that the synthetic immunomodulator Murabutide inhibits human immunodeficiency virus type 1 (HIV-1) replication at multiple levels in macrophages and dendritic cells. The present study was designed to profile the activity of Murabutide on CD8-depleted phytohemagglutinin-activated lymphocytes from HIV-1-infected subjects and on the outcome of HIV-1 infection in severe ...