Monocyte tumor cell line PU5-1.8 does not normally produce colony-stimulating activity (CSA) required by granulocyte and macrophage progenitors to proliferate and mature in agar. However, CSA is induced in the culture line by as little as 10 ng/ml endotoxic lipopolysaccharide (LPS), with maximum CSA production and release to the medium between 2 and 3 days of incubation. Derived lipid A, but no...

Background: Mushrooms have been valued as high tasty nutritional and nutraceutical food throughout the world. At present 270 species of mushrooms are known to have various nutritional and therapeutic properties. Polysaccharides are the primary content of mushrooms that are used for their pharmaceutical properties as immunostimulators. Objectives: Here, Mushrooms were screened for useful polysa...

Purpose. To analyze the productive-biological and biochemical parameters of sturgeon larvae fry under conditions introduction synthetic (Levamisole) organic (Chitosan) immunostimulants into their diet. evaluate effect supplements on stability homeostatic processes based analysis enzyme activity. Methodology. The study was carried out juvenile hybrid besters (♀ Huso huso х ♂ Acipenser ruthenus) ...

Introduction: Sungkai (Peronema canescens, Jack.) contains polysaccharides, terpenoids, alkaloids, and polyphenols which have pharmacological activity as immunostimulants. Objective: This study aimed to see how the effect of extract an immunostimulant agent was carried out in vitro vivo. Materials Methods: conducted using two methods, namely vivo vitro. In research method test phagocytic capaci...

Either of two immunostimulating factors (lpr, lipopolysaccharide) enhanced the pathogenic autoimmune responses of MRL/n mice, but the serologic and immunopathologic characteristics differed. In contrast, either factor acting alone, caused minimal immunopathology in normal mice, despite autoantibody induction. Combined immunostimulation, however, caused fatal glomerulonephritis in normal-backgro...

TMAZ, natural zeolite clinoptilolite with enhanced physicochemical properties, have been shown to possess antioxidant activity in humans. Modes of immunomodulation including superantigen-like action of ingested zeolite and perspectives of immunotherapeutic approaches for malignant and infectious diseases and autoimmune disorders are discussed. Accumulating evidence from preclinical studies and ...

1-(6-Bromo-3-methyl-1,3-thiazolo[3,2-alpha]benzimidazol-2-yl)ethanone (2) was prepared by bromination at ambient temperature of 1-(3-methylthiazolo[3,2-alpha]benzimidazol-2-yl)ethanone (1). The structure of 2 was determined by single-crystal X-ray diffraction. The precursor 5 was synthesized by heating a mixture of acetyl 2 and bromine. Various 2-substituted 6-bromo-3-methylthiazolo[3,2-alpha]b...