نتایج جستجو برای: immunosuppressive agent
تعداد نتایج: 273767 فیلتر نتایج به سال:
Frentizole, 1-(6-methoxy-2-benzothiazolyl)-3-phenyl urea, a new immunosuppressive agent, and azathioprine were administered subcutaneously at predetermined immunosuppressive dose levels of azathioprine and up to 50 times an immunosuppressive dose level of Frentizole. After 10 days of treatment at these dose levels, the experimental groups were inoculated intraperitoneally with Pseudomonas aerug...
A successful pregnancy following renal allotransplantation is reported. Until now azathioprine has been used as the standard immunosuppressive agent in such cases. Because of the potential teratogenicity of azathioprine, low doses of cyclosporin A, a new immunosuppressive drug, was used in our pregnant recipient. We present the management and the outcome of the pregnancy, as well as the hormona...
TACROLIMUS is a potent immunosuppressive agent. It has been reported to have superior immunosuppressive efficacy when compared with the standard formulation of cyclosporine (CyA).1 based on its ability to rescue patients with failing allografts under CyA-based therapy,2.3 lower rejection rates when used as a primary immunosuppressive agent.45 and longer projected half-life." However. there have...
Since its introduction in 1979, CyA has been the immunosuppression agent of choice in clinical transplantation of all solid organs.1 More recently, a novel new immunosuppressive agent, FK 506, has been introduced in experimental transplantation.2 Most recently, it also has been introduced into clinical liver transplantation. Both agents appear to be T cell-specific and induce their immunosuppre...
FK 506 was used as a primary immunosuppressive agent in 125 cases of renal transplantation in a randomized trial comparing FK 506/prednisone with FK 506/azathioprine/prednisone. With a mean follow-up of 5.5 +/- 2.5 months, there has been a 6-month actuarial patient survival of 99% and graft survival of 88%. There is no difference thus far between the two-drug and three-drug groups, although the...
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