The effect of Lambda-cyhalothrin on the immune response was studied in rabbits exposed to the insecticide via food at concentrations of 1373.23, 686.76 or 343.38 ppm (equivalent to 1/10, 1/20 and 1/40 oral LD50, respectively) for 8 weeks. The humoral immune response was measured by determination of the antibody titre against sheep red blood cells (SRBC), a T cell dependent antigen. Moreover, th...

A workshop cosponsored by the National Institute of Environmental Health Sciences and the National Institute for Occupational Safety and Health was convened in Washington, DC, on 17-18 October 2001 with the goal of developing a consensus document on the most appropriate experimental approaches and assays available to assess developmental immunotoxicity. The work group was composed of scientists...

The immune system plays a crucial role in maintaining health; however, accumulating evidence indicates that this system can be the target for immunotoxic effects caused by a variety of chemicals including the environmental pollutants of polychlorinated biphenyls, chlorinated dibenzo-p-dioxins, pesticides, and heavy metals. Adverse chemical-induced immunomodulation, which is studied within the d...

This study investigated the immunotoxic potentials of raw and simulated leachates from Olushosun municipal solid waste landfill in rat using quantitative leucocyte and differential counts. Blood samples of rats intraperitoneally exposed to 1 – 25 % concentrations of each of the leachate samples for 48 hours were examined post treatment for leukocyte and differential counts. Compared to the nega...

AIM This study was planned for determination the toxic effect of thiamethoxam (TMX) in immunized mice with Brucella abortus culture filtrate antigen (CFBAgs) (as a vaccine) and its role of TMX on decrease activity of B. abortus antigen on eliciting of humoral and cellular immunity. MATERIALS AND METHODS To achieve these goals 60 female mice were used, 7-8 weeks age, they were divided equally ...

The present review deals with effects of vitamin C on lead intoxicated developing thymus in mice .In the world of environmental health and medicine, lead exposure remains one of the most important problems in terms of prevalence of exposure and public health impact. Previous research has shown that every level of lead exposure is dangerous to animals and humans. Thus lead toxicity continues to ...