Любой процесс, участвующий в жизнедеятельности общества, можно рассматривать с нескольких сторон, направлений, причем они могут быть иметь разное отношение друг к другу: кардинально противоположны, вытекающие из друга и т.д. В данной статье мы рассмотрим процессы индивидуализация социализация личности контексте образования выясним, как взаимосвязаны другом. Актуальность темы заключается том, чт...

Polyglycylation is a posttranslational modification that generates glycine side chains on proteins. Here we identify a family of evolutionarily conserved glycine ligases that modify tubulin using different enzymatic mechanisms. In mammals, two distinct enzyme types catalyze the initiation and elongation steps of polyglycylation, whereas Drosophila glycylases are bifunctional. We further show th...

Members of the oxysterol binding protein (OSBP) family are involved in diverse biological processes, including non-vesicular sterol transport and vesicle trafficking. The mechanisms by which OSBPs integrate functionally with developmental and physiological processes remain elusive. Here, we report the in vivo analysis of OSBP function in the model organism Drosophila. Osbp mutants are male-ster...

Antihypertensive drug classes are usually classified as 1st, 2nd, 3rd, and 4th or 5th choice to help physicians select the drug most suitable for treatment initiation among the very many classes available to lower blood pressure (BP) in patients with a BP elevation. However, this approach was appropriate decades ago when several drugs had inconveniences that made their use in monotherapy inadvi...

Workplace safety and productivity will be enhanced considerably with the development and application of individualized sleep and performance prediction models. These are models that predict an individual’s operational performance based on his/her unique sleep schedule, individual sleep requirements, and individual pattern of responses to sleep loss across a variety of cognitive performance doma...