1 Caffey J, Silverman W. Infantile cortical hyperostosis. Preliminary report in a new syndrome. AJR 1945;54:1. 2 Van Buskirk FW, Tampas JP, Peterson OS Jr. Infantile cortical hyperostosis. An enquiry into its familial aspects. AJR 1961;85:613. 3 Finsterbush A, Rang M. Infantile cortical hyperostosis. Followup of 29 cases. Acta Orthop Scand 1975;46:727. 4 Jackson DR, Lyne ED. Infantile cortical ...

Infantile spasms is an epileptic encephalopathy of early infancy with specific clinical and electroencephalographic (EEG) features, limited treatment options, and a poor prognosis. Efforts to develop improved treatment options have been hindered by the lack of experimental models in which to test prospective therapies. The neuropeptide adrenocorticotropic hormone (ACTH) is effective in many cas...

hemangioma is the most common benign cutaneous vascular tumor in infants and children. the hemangioma incidence in the neonates is 2% to 3% that increases to 10% in those younger than one year of age. before introduction of propranolol in 2008, different medications such as systemic corticosteroids and vincristine, with different side effects, were used for years. since then, over 200 studies c...

the role of enterotoxigenic e.coli as a causative agent in diarrheal disease was studied among 100 cases of infant and children 0-2 years of age. routine bacteriological methods were used for identification enteropathogenic e.coli, salmonella, shigella and vibrio cholera. the ability of e.coli strains to produce toxin was assayed in animal models (rebbit-ileal loop and suckling mice) and in tis...

background considering the inadequacies of current therapeutic regimens for infantile spasms (is), and the frequent and serious side effects of  some regimens, the ongoing search for more enhanced protocols is understandable. materials and methods: we have compared the therapeutic and adverse effects of vitamin b6 given in high doses with those of prednisolone in a randomized controlled clinica...

AIM To describe how fetal growth and gestational age affect infantile colic, while considering other potential risk factors. STUDY DESIGN A population based follow up study of 2035 healthy singleton infants without any disability born to Danish mothers. Information was collected by self administered questionnaires at 16 and 30 weeks of gestation, at delivery, and 8 months post partum. Infanti...

While >200 types of etiologies have been shown to be involved in the pathogenesis of infantile spasms, the pathophysiology of infantile spasms remains largely elusive. Pre-natal stress and hypothalamic-pituitary-adrenal axis dysfunction were shown to be involved in the development of infantile spasms. To test the genetic association between the CRHR1 gene, which encodes the corticotrophin-relea...

OBJECTIVE To investigate the associations between use of nicotine replacement therapy (NRT) and smoking during pregnancy and infantile colic in the offspring. METHODS We used data from maternal interviews (from pregnancy and at 6 months post partum) from the Danish National Birth Cohort (1996-2002). We included 63 128 live-born singletons with complete information on nicotine exposure during ...

PURPOSE To compare development of acuity in patients with isolated infantile nystagmus and infantile nystagmus associated with a visual sensory defect. METHODS Visual acuities in 57 children (1 month to 4 years of age) with infantile nystagmus were assessed by using Teller acuity cards oriented vertically during binocular viewing. Twenty-two had isolated infantile nystagmus, 21 had albinism, ...

Background: Infantile spasms (IS) represent an age-specific epileptic disorder of infancy and early childhood. Children with infantile typically exhibit along the electroencephalographic (EEG) pattern known as roceededica. Although rare, 1.6 to 4.5 per 10,000 live births, IS is a significant because association developmental delay or regression, high mortality rate, refractoriness conventional ...