Bipod nettle Utrica dioica L has therapeutic properties in treatment of human chronic diseases such as anemia, joints pain and skin diseases. In this research the major components of extracts in different parts of plant (root, stem and leaf) were identified by gas chromatography (GC) apparatus. Twenty compounds were identified, the most important of which were Neophytadiene (25.21%), Phtaleic a...

brain death is associated with increased inflammatory cytokines levels and poor graft quality to transplant. we aimed to evaluate the impact of ascorbic acid (aa) on the inflammatory status of brain-dead donors (bdds). forty bdds were randomly divided into two groups. donor treatment (n=20) consisted of 100 mg/kg aa infusion 6 hours before donor operation and subsequent infusion of 100 mg/kg/p6...

Background: This study was designed to investigate the effects of Urtica dioica on liver ischemia reperfusion injury in rats. Methods: Thirty male Wistar-albino rats were used in this experimental study. Animals were divided into three groups as sham operated (group 1), control (group 2), and Urtica dioica treatment group (group 3). Urtica dioica 2ml/kg were administered intraperitoneally befor...

Urtica dioica is an ethnobotanically and medicinally important Complementary and Alternative Medicine (CAM) plant worldwide and in Turkey; 90 % of herbal CAM applications depend on it in Turkey. It has a wide range of habitats in nearly all continents. It is found in all three phytogeographical regions in Turkey (Euro-Siberian, Irano-Turanian, Mediterranean) with high adaptivity to heterogeneou...

introduction: neuroinflammation may play as an important risk factor in progressive degeneration of dopaminergic cells. antioxidants have protective effects against free radicalsinduced neural damage in parkinson’s disease (pd). in the present study, we examined the effects of ellagic acid (ea) on locomotion and neuroinflammatory biomarkers in a rat model of pd induced by 6-hydroxidopamine (6-o...

background: considering the increasing trend of obesity, especially in developing countries such as iran, and the role of inflammatory factors and insulin resistance (ir) in the occurrence of obesity?related complications as well as the safety of some agents such as folic acid and metformin, this clinical trial was designed to investigate the effect of metformin and folic acid on inflammatory f...

The effects of hydroalcoholic (80% ethanol-20% water) extract of Urtica dioica L. on microsomal aniline 4-hydroxylase (A4H) were investigated in the liver of Swiss albino mice (8- 10-weeks-old) treated with two doses (50 and 100 mg/kg body weight, given orally for 14 days ). The activities of A4H showed a significant increase in the liver at both dose levels of extract treatment. The hydroalcoh...

Problem statement: Urtica pilulifera L. (Urticaceae), has long been used for the treatment of various aliments including diabetes. Diabetes is a metabolic disorder characterized by hyperglycemia which has a deleterious effect on all systems including reproductive system of animals. Therefore, the current study was designed to investigate the effects of Urtica pilulifera on the reproductive syst...

OBJECTIVES To evaluate the effects of Urtica dioica on hepatic ischemia-reperfusion injury. METHODS Thirty adult male Wistar albino rats were divided into three groups: sham group (group 1), control group (group 2), and Urtica dioica group (group 3). All the rats were exposed to hepatic ischemia for 60 min, followed by 60 min of reperfusion. In group 2, a total of 2 ml/kg 0.9% saline solution...