a simple and efficient one-pot three-component synthesis of the biologically important spirooxindole-4h-pyrans was carried out by the reaction of isatin, activated methylene reagents, and 4-hydroxycoumarin in aqueous medium. sba-pr-nh2 was found to be an efficient heterogeneous nanoporous solid basic catalyst (pore size of 6 nm) which can be easily handled and removed from the reaction mixture ...

background and objective: although there are reports in the literature on the antimicrobial effects of green tea, the effect of black tea, the most common beverage in iran, on growth of bacteria, such as streptococcus pyogenes, has not been studied extensively. this study was undertaken to determine the inhibitory effect of black tea on the growth of streptococcus pyogenes in vitro and compare ...

results in total, 73 isolates were collected and diagnosed as s. pneumoniae. isolates were susceptible to ofloxacin 95.9%, vancomycin 93%, penicillin 78%, trimethoprim-sulfamethoxazole 61.6%, ceftriaxone 53.5%, meropenem 52%, cefotaxime 46.5%, and erythromycin 8.2%. of the 15 prsp isolates, the pbp2b gene was identified in 12 (80%). in 1 penicillin-intermediate s. pneumoniae isolate the pbp2b w...

?-amylase inhibitory activities of ethanol extracts from six selected iranian salvia species (s. hydrangea dc., s. hypoleuca benth., s. officinalis l., s. reuterana boiss., s. verticillata l. and s. virgata jacq.) were examined, using in vitro model. in addition, antioxidant capacities (dpph• radical scavenging) and total flavonoid cotents of the extracts were also determined. the results showe...

abstract       background and objective: enterococci are relatively nonvirulent bacteria that rarely cause disease. antimicrobial treatment of enterococci is often challenging due to their antibiotic resistance. this study aimed to investigate the antibacterial activity of aqueous extract of garlic against enterococcal isolates.     methods: in this descriptive study, 120 enterococcus isolates ...

background: the aim of this study was to determine the occurrence of virulence determinants and vancomycin- resistant genes among enterococcus faecalis and e. faecium obtained from various clinical sources. methods: the study was performed on the 280 enterococcal isolated from clinical specimens in hamadan hospitals, western iran in 2012-14. antibiotic susceptibility testing was performed using...

objective(s): the aim of the present study was to prepare, characterize, and evaluate solid lipid nanoparticles (slns) containing zataria multiflora essential oil (zeo). materials and methods: in this study, z. multiflora essential oil-loaded solid lipid nanoparticles (ze-slns) were prepared to improve its efficiency in controlling some fungal pathogens. slns containing z. multiflora essential ...

abstract  background: despite the long-standing association of macrophage migration inhibitory  factor (mif) with delayed-type hypersensitivity response, the potential role  of mif in chronic allograft nephropathy is unknown. the association between upregulation of mif expression, macrophage and t cell infiltration and the severity of  chronic allograft nephropathy suggests that mif may be an i...

background: in recent years, drug resistance to human pathogenic fungi has been increased. medicinal plants are one way to overcome antibiotic resistance. the aim of this study was to evaluate the antifungal and inhibitory activity of five medicinal plants on the growth of candida albicans. methods: this study was done in the microbiology lab of shahid bahonar university of kerman, iran in 2015...

introduction: gonadotropin inhibitory hormone (gnih) and agouti-related peptide (agrp) are orexigenic peptides expressed in the arcuate nucleus (arc) of the hypothalamus in the ewe. in addition, effects of gnih and agrp on the regulation of gonadotropin releasing hormone secretion have been shown in some mammals. the objective of the present study was to investigate the coexpression of gnih and...