conclusions although previous studies have shown that a-g transition mutations in 23 srrna gene (domain v) are the main reason for the occurrence of high level macrolides resistance in b. pertussis, however, the mentioned single nucleotide polymorphisms (snps) have not been detected in our resistant strain. this is the first report of high level macrolide resistant b. pertussis, without snps in...

abstract background: a surgical site infection (ssi) is the most common nosocomial infection after surgery and is the third most common infection in hospitalized patients. the aim of this study was to asses minimum inhibitory concentration (mic) of the causing agents of ssi and antimicrobial susceptibility patterns. methods: this cross-sectional study was done in three referral hospitals in nor...

in this study, we investigated the antifungal effects of silver nanoparticles (ag-nps) on candida albicans (atcc 5027), saccharomyces cerevisiae (atcc 5027). investigating method by using minimum inhibitory concentration (mic) technique, some of drugs including amphotericin b, fluconazole and synthesized ag-nps have been obtained on the fungi and the changes on membrane reactions of yeasts have...

background: in this study, the efficacy of nitazoxanide in the treatment of helicobacter pylori isolates, which were resistant to metronidazole, was examined.   methods: one hundred twenty two patients who underwent endoscopy examinations at kasra and laleh hospitals in tehran from november 2014 to july 2015 were enrolled. helicobacter pylori strains were isolated from the patients’ endoscopy b...

emergence of resistance among pathogenic bacteria against available antibiotics is posing a great challenge to the current world. thus, there is a great need to discover novel antibiotics. traditional plants have been proved to be novel source in the search of antimicrobial compounds. the current study pertained to the susceptibilities of some clinically significant bacterial species to various...

background: in this study, the efficacy of nitazoxanide in the treatment of helicobacter pylori isolates, which were resistant to metronidazole, was examined.   methods: one hundred twenty two patients who underwent endoscopy examinations at kasra and laleh hospitals in tehran from november 2014 to july 2015 were enrolled. helicobacter pylori strains were isolated from the patients' endoscopy b...

results of total 60 s. aureus isolates, 51 (85%) were mrsa, and of 60 cons, 7 (11.66%) were mrcons. the results showed that the mic of chlorhexidine for all 120 isolates was 1-16 μg/ml. 15 (12.5%) isolates carried qaca/b gene, 26 (21.7%) carried qacc gene, and 38 (31.7%) carried smr gene. conclusions maintenance of mrsa isolates in the attendance of low amounts of antiseptics could result in th...

abstractpropionibacterium acnes is propounded as one of the significant factors in occurrence of acne. today, due to development of the antibiotic resistance, most of the acne treatments are faced with failure. in order to determine the antibiotic resistance of the p.acnes strains isolated from the patients with acne, this research has been carried out. 70 samples collected using microbial cult...

background: one of the main causes of sexually transmitted diseases is group b β- hemolytic streptococci (gbs) multiplying in the genital tracts. penicillin is the most common drug for the treatment of infections caused by these bacteria, but in patients suffering from penicillin allergy, erythromycin and clindamycin are used as alternative therapeutic drugs against gbs. recently, resistance to...

we consider of the antimicrobial activity on the ag nanoparticles(ag nps) aqueous solutions, which was prepared using a stabilizer, such as poly(n vinyl 2 pyrrolidone pvp , for staphylococcus aureus) s aureus and escherichia coli e coli by measuring the minimum inhibitory concentration mic . antimicrobial effect of ag nps for s aureus and e coli was investigated using disk diffusion method also...