BACKGROUND The objective of this study was to identify the impact of diabetes and related comorbidities, namely chronic renal failure, peripheral vascular disease, and low ejection fraction (<35%), on long-term survival of patients undergoing coronary artery bypass graft surgery. METHODS AND RESULTS A unicenter study was conducted on 9125 survivors of isolated coronary artery bypass graft sur...

The term "Diabetes mellitus" encompasses a heterogeneous group of disorders characterized by insulin hyposecretion and/or insensitivity. Type 1 (insulin-dependent) diabetes mellitus is thought to have an autosomal recessive inheritance and an autoimmune pathogenesis, exhibited by lymphocytic insulitis. The latter may be triggered by viruses or chemical agents. Type 2 (non-insulin-dependent) dia...

results this study shows the prepared gene construct is inducible by glucose. gene expression of preproinsulin was observed in muscle tissue of rabbits. conclusions these finding indicated that research in diabetes mellitus gene therapy could be performed on larger animals. objectives the purpose of this study was to construct glucose inducible insulin gene plasmid and use it in the muscle tiss...

non-insulin dependent diabetes mellitus (niddm) is a common disease entity in patients with coronary artery disease (cad). diabetic ketoacidosis (dka) is not only one of the major complications of diabetes mellitus but also a significant challenging clinical entity for the patients undergoing any elective or emergency surgery. coronary artery bypass grafting (cabg) being done in a patient with ...

abstract introduction: in recent years, many studies employed and found an association between type 2 diabetes mellitus and colorectal cancer. although increased risk of colorectal cancer in individuals with non insulin dependent diabetes mellitus (niddm) has been observed in previous studies, limited information is available on the colorectal cancer associated with niddm in iran. the purpose o...

OBJECTIVES We sought to determine whether the antioxidant vitamin C improves endothelium-dependent vasodilation of forearm resistance vessels in patients with insulin-dependent diabetes mellitus. BACKGROUND Endothelium-dependent vasodilation is impaired in patients with diabetes mellitus. Oxidatively mediated degradation of endothelium-derived nitric oxide contributes to abnormal endothelium-...

Diabetes mellitus comprises a heterogeneous group of disorders characterized by high blood glucose levels. Four major types of diabetes have been defined by the National Diabetes Data Group (NDDG) and the World Health Organization (WHO): insulin-dependent diabetes mellitus (IDDM), non-insulin-dependent diabetes mellitus (NIDDM), gestational diabetes mellitus (GDM), and diabetes secondary to oth...

concurrent disorders with diabetes mellitus is one of the most challenging subject. our knowledge of the most common concurrent disorders in diabetic dogs may be useful in diagnosis of these disorders and better treatment of diabetic dogs. in this study diabetes mellitus was diagnosed in a 7-year-old male german shepherd dog, based on clinical and laboratory findings. following the diagnosis of...

It has been shown that an adenine (A) to guanine (G) transition at position 3243 of the mitochondrial transfer RNA(tRNA)leu(UUR) gene is associated with a subgroup of diabetes mellitus. Therefore, we screened for this transition in 86 patients with non-insulin-dependent diabetes mellitus (NIDDM) in which two or three generations were affected with diabetes, in 14 patients with insulin-dependent...

background: previous studies have demonstrated that patients with insulin-dependent diabetes mellitus (iddm) have a high prevalence of osteopenia.  hypercalciuria has also been well documented in human diabetes and many children with insulin-dependent diabetes mellitus have short stature.   objective: to investigate the relationship of hypercalciuria and hyperphosphaturia with growth retardatio...