A class 1 integron was detected in a single multidrug-resistant strain of enterotoxigenice Escherichia coli (ETEC) O159 after examination of 23 clinical E. coli isolates. This isolate was resistant to streptomycin, kanamycin, gentamicin, chloramphenicol and ampicillin. Sequencing of the class 1 integron identified three-gene cassettes. The first is the streptothricin acetyltransferase gene, sat...

Recently another MITE-like structure, called the integron mobilization unit (IMU), has been described flanking a defective class 1 integron harbouring a carbapenem resistance gene, blaGES-5, in a clinical Enterobacter cloacae strain. Although the IMU sequence is not related to the MITE reported in our study, IMU-based mobilization of the integron could be demonstrated using a transposase provid...

Pseudomonas aeruginosa is an opportunistic human pathogen that causes nosocomial infections. This bacterium is characterized by inherent resistance to a wide variety of antimicrobials; the inherent resistance is always mediated by antibiotic resistance genes (3, 10). A genetic element, the integron, is potentially a major agent in the dissemination of multidrug resistance among gram-negative ba...

Background and Aim: The increasing prevalence of resistance (MDR) Enterobacteriaceae in Indonesia has caused concern regarding human health. Citrobacter freundii reportedly targets the gastrointestinal tract animals is a common cause foodborne diseases associated with diarrhea, peritonitis, meningitis, brain abscess, bacteremia, urinary infection. This study aimed to estimate MDR presence Class...

Abstract Background Group II introns are mobile genetic elements used as efficient gene targeting tools. They function both ribozymes and retroelements. IIC the only class reported so far to be associated with integrons. In order identify group linked integrons CALINS (cluster of att C sites lacking a neighboring integron integrase) within halophiles, we mined for in 28 assembled metagenomes fr...

pseudomonas aeruginosa is among the most important pathogens in the nosocomial infections. a genetic mobile element, the integron, is one of the major agents involved in dissemination of multi-drug resistance among gram negative bacteria. during a descriptive study from october 2009 to august 2010, some 130 p. aeruginosa clinical isolates were collected from different wards of three hospitals i...

Background and Aims: The indiscriminate use of antibiotics can lead to antibiotic resistance in the treatment of infections caused by bacteria such as Pseudomonas aeruginosa. The presence of integrons in Pseudomonas is clearly associated with multidrug resistances. Therefore, this study aimed at tracking class I, II and III integrons of antibiotic-resistant isolates of Pseudomonas aeruginosa th...

Background and Aims: Integrons as mobile genetic elements are located on the chromosome or on a plasmid in bacteria. Integrons play a main role in the dissemination of antibiotic resistance genes among different families of bacteria. The aim of this study was to identify the prevalence of class 1 integron in Klebsiella pneumoniae isolates from hospitals of Sanandaj, Kurdistan province, Iran. M...

Antibiotic resistant E. coli in the animal gut can promote transfer of antibiotic resistance between and human. In order to enforce National Action Plan Bangladesh, it is imperative detect presence harbouring Class 1 integrons that potentially genes among bacteria. Previously used primers pairs were a multiplex PCR successfully species-specific amplicon integron 57% isolates. Plasmid was absent...

BACKGROUND/AIM Pseudomonas aeruginosa is the cause of 10% of hospital-acquired infections. The organisms are often multidrug- resistant, mediated mostly by antibiotic-resistant integrons. The aim of this research was to study integron carriage and its association with multidrug resistance in burn and nonburn clinical isolates of P. aeruginosa. MATERIALS AND METHODS A total of 112 P. aeruginos...