Mme A.N, patiente de 58 ans, diabétique type 2 depuis 20 ans, ayant consulté en dermatologie pour un intertrigo sous mammaire (A), mise sous traitement avec mauvaise observance thérapeutique. La patiente est admise un mois par la suite aux urgences pour la prise en charge d'un état de choc septique avec une décompensation acéto-cétosique. L'examen Clinique a retrouvé une patiente en trouble de ...

Diabetic foot infections are one of the most dreadful and costly complications of diabetes. Efforts have recently focused on preventive measures. The balance of moisture in the neuropathic foot is critical and challenging. Whilst the interdigital areas should be kept dry to prevent maceration and subsequent softening and thinning of the skin other areas of the foot should be managed for optimal...

BACKGROUND Dichelobacter nodosus is the main causative agent of ovine footrot, and there are strong indications that the bacterium can be transferred to cattle grazing on the same pasture as sheep. The aim of this study was to investigate if benign and virulent D. nodosus strains isolated from sheep can be transferred to the interdigital skin of cattle under experimental conditions. Further, we...

Fine structural study of interdigital membranes during formation of the digits of the duck foot reveals that the interdigital necrosis is accompanied by a high deposition of collagenous material in the epithelio-mesenchymal interface, rupture of the basal lamina and detachment of ectodermal cells into the amniotic sac. These changes are similar to those observed in the regressing interdigital m...

phytosis complex." 2,3 A bacterial and fungal culture may thus be necessary to identify all nail and foot pathogens. A clue that a patient has a significant bacterial infection is green discoloration of the nail, as in our patient. Unfortunately, because of the faster growth rate of bacteria, isolation of fungi is often not possible. The inability to isolate a fungus because of bacterial overgr...

Background: Postburn dorsal and palmar interdigital commissural contracture is one of the most common complications of hand burns which restricts finger motion and presents a serious cosmetic defect. Many techniques and flaps have been suggested, and research continues for more effective techniques as the problem has not been solved. Methods: Anatomy of scar interdigital commissural contracture...

Digit formation during vertebrate limb development is a well-known example of programmed cell death. We have used this system to analyze whether the formation of the interdigital necrotic zone in mouse autopods is linked with the expression of BAG-1, a gene with an anti-death activity. Here, we demonstrate that during development of mouse autopods, BAG-1 expression is downregulated upon the ini...