Abstract The aim of this study is to identify the active compounds essential oil extracted from Pinus densiflora (Sieb. et Zucc.) wood using hydrodistillation method and evaluate their anti-inflammatory activity. chemical composition was identified by GC–MS analysis, its activity assessed investigating effect on expression interleukin-4 (IL-4), interleukin-13 (IL-13), ? -hexosaminidase in lipop...

To observe the pro- and anti-inflammatory cytokine (TNF-α, IL-4, IL-6, IL-10) secretion from cultivated peripheral blood mononuclear cells (PBMCs) for 48h. Blood samples were obtained 42 women patients of Nadezhda Women’s Health Hospital after signing written informed consent. For PBMC isolation, 9 ml heparinised whole each patient processed by density gradient centrifugation using Pancoll (P04...

background: the aim of this study was to determine the th1 and th2 serum cytokines, in patients with psoriasis and to com pare their cytokine levels with those of normal control subjects. methods: serum levels of interferon-gamma (ifn-γ), interleukin-2 (il-2), interleukin-4 (il-4), and interleukin-10 (il-10) were measured by enzyme linked immunosorbent assay in 40 patients with psoriasis and in...

Interleukin-4 (IL-4) plays a key role in atopic diseases. It coordinates T-helper cell differentiation to subtype 2, thereby directing defense toward humoral immunity. Together with Interleukin-13, IL-4 further induces immunoglobulin class switch IgE. Antibodies of this type activate mast cells and basophilic eosinophilic granulocytes, which release pro-inflammatory mediators accounting for the...