It is often difficult to assess small bowel recovery in adults with coeliac disease on a gluten-free diet (GFD). This prospective study compares changes in intestinal permeability with changes in intestinal biopsy at various intervals after commencing a GFD. Intestinal permeability was measured by lactulose/rhamnose absorption from 1 week to 24 months after commencing a GFD. Intestinal morphome...

BACKGROUND Fermentable dietary fibre has many effects on the gastrointestinal tract. One is to alter epithelial crypt cell proliferation, especially in the colon. A discrepancy between epithelial cell production rates and intestinal weights has been noted previously: crypt cell production rates only increase if bacterial fermentation occurs, but intestinal wet weight can increase in the same an...

Abstract RATIONALE Inflammatory bowel disease (IBD) comprises a group of intestinal disorders, including ulcerative colitis and Crohn's disease. Intestinal fibrosis, as result chronic inflammation, is common complication in IBD. High treatment failure rates associated with existing interventions indicate high unmet need for more effective drugs to improve the management outcomes Consequently, t...

Abstract Background Inflammatory bowel disease (IBD) comprises a group of intestinal disorders, including ulcerative colitis and Crohn's disease. Intestinal fibrosis, as result chronic inflammation, is common complication in IBD. High treatment failure rates associated with existing interventions indicate high unmet need for more effective drugs to improve the management outcomes Consequently, ...

INTRODUCTION Bacterial translocation is the invasion of indigenous intestinal bacteria through the gut mucosa to normally sterile tissues and internal organs. Schistosomiasis may cause alterations in the immune system and damage to the intestines, portal system and mesenteric lymph nodes. This study investigated bacterial translocation and alterations in the intestinal microbiota and mucosa in ...

he incidence of the diverticulum of the small bowel varies from 0.2-1.3% in autopsy studies to 2.3% when assessed on enteroclysis. it occurs mostly in patients in the 6th decade of their life. of all the small bowel diverticuli, jejunal diverticulum is the most common type. this rare entity is usually asymptomatic. however, they may cause chronic non-specific symptoms for a long period of time ...