BACKGROUND AND PURPOSE Cerebral vasospasm remains a major problem in patients recovering from aneurysmal subarachnoid hemorrhage despite advances in medical, surgical, and endovascular care. Our purpose was to assess the efficacy of intra-arterial nimodipine, a calcium-channel blocker acting mainly on cerebral vessels, in preventing delayed neurologic deficits in patients with symptomatic vasos...

oxygen is an essential part of the most important metabolic pathways in aerobic organisms. oxygen delivery is merely dependent on blood, rendering blood loss a devastating event. traumatic pre-hospital liver bleeding is a major cause of early trauma deaths in human and animals, with no established therapeutic method yet. increasing intra-abdominal pressure (iap) has been shown to reduce liver b...

introduction: traumatic brain injury is considered as the major cause of mortality and hospitalization of about ten million people across the globe. most of these patients are young and active people suffering disabilities. tranexamic acid (txa) therapy is commonly used to reduce blood loss and need for blood transfusions in surgical cases. this study aimed at investigating the effect of tranex...

while a wide array of pathological changes occur in cerebral arteries following subarachnoid hemorrhage (sah), the most consistent is endothelial damage. since the endothelium normally modulates reflexes that influence vascular tone, any damage to it may represent a significant contributor to cerebral vasospasm following sah. this experimental study investigates the correlation between endothel...

BACKGROUND For those who initiate chronic dialysis, knowing what proportion will experience 3-year outcomes of hemorrhage with hospitalization informs patient prognosis, disease impact, and the planning of trials and programs to prevent events. OBJECTIVES We examined the incidence of hemorrhage and related gastrointestinal endoscopic procedures in incident older dialysis patients and stratifi...

Background: Intracerebral hemorrhage is a complication of thrombolytic therapy in stroke patients. Furthermore, Cerebral Amyloid Angiopathy (CAA), which itself can cause hemorrhage, may be risk factor for thrombolysis related intracerebral hemorrhage.

Subarachnoid hemorrhage is typically due to an aneurysmal rupture. Cerebral venous thrombosis a rare cause, especially if the clinical presentation atypical. We report patient with unusual acute headaches, entirely normal physical examination. His cerebral MRI, and angio-MRI documented associated subarachnoid hemorrhage. The outcome was favorable anticoagulant treatment.

BACKGROUND Cerebral vasospasm is one of the leading courses for disability in aneurysmal subarachnoid hemorrhage. Effective treatment of vasospasm is therefore one of the main priorities for these patients. We report about a case series of continuous intra-arterial infusion of the calcium channel antagonist nimodipine for 1-5 days on the intensive care unit. METHODS In thirty patients with an...

BACKGROUND The failures of recent studies intended to prevent cerebral vasospasm have moved the focus of research into delayed cerebral ischemia away from cerebral artery constriction towards other mechanisms. Recent accumulating evidence has suggested that early brain injury is also involved in the development of delayed cerebral ischemia, and that hydrogen can prevent early brain injury. Ther...