a simple, selective and sensitive method for the determination of trace amount of titanium (iv) based on its catalytic effect on methylene blue- ascorbic acid redox reaction has been reported. the reaction was followed spectrophotometrically by measuring the change in absorbance of methylene blue at 665 nm, 5 minutes after the initiation of the reaction. in this study experimental parameters we...

nafion is a perfluorinated anionic polyelectrolyte. the increasing popularity of nafion for the fabrication of redox polymer modified electrodes in recent years arises from easy fabrication, good electrical conductivity and high partition coefficients of many redox compounds in nafion. to investigate the production of nano-compositions by mixing electron transfer material and nafion polymer for...

peritoneal adhesions are challenging in abdominal surgery. in spite of different kinds of treatments still no definitive and effective treatment is suggested. to determine the prevention effects of intraperitoneal (ip) methylene blue in post surgical adhesion formation 44 rabbits were randomly divided in two groups of equal number. group i received an intra peritoneal injection of a 1% suspensi...

The response of the hexose monophosphate shunt in erythrocytes was studied with the ionization chamber-electrometer apparatus to measure continuously 14CO2 derived from 14C-labeled substrates. The effect of methylene blue at high (0.1 mM) and low (1 muM) concentrations was evaluated under different gas mixtures; air, carbon monoxide, and 6% carbon monoxide in air. The latter gas mixture results...

In neurodegenerative disorders, abnormally hyperphosphorylated and aggregated tau accumulates intracellularly, a mechanism which is thought to induce neuronal cell death. Methylene blue, a type of phenothiazine, has been reported to inhibit tau aggregation in vitro. However, the effect of methylene blue in vivo has remained unknown. Therefore, we examined whether methylene blue suppresses abnor...

introduction: the topical and intradermal photodynamic therapy (pdt) effect of methylene blue (mb) using light-emitting diode (led) as light source (mb/led-pdt) in the treatment of lesions of american cutaneous leishmaniasis (acl) caused by leishmania braziliensis in hamsters were investigated. methods: hamsters were infected in the footpad with 4×107 promastigotes of l. braziliensis and divide...

Neural stem cell-based treatment holds a new therapeutic opportunity for neurodegenerative disorders. Here, we investigated the effect of methylene blue on proliferation and differentiation of rat neural progenitor cells (NPCs) both in vitro and in vivo. We found that methylene blue inhibited proliferation and promoted quiescence of NPCs in vitro without affecting committed neuronal differentia...

Methylene blue-treated fresh-frozen plasma (MB-FFP) is mainly used in Europe. The advantage of the methylene blue system is that units can be treated individually. The combined action of methylene blue and illumination is a photodynamic process preventing viral RNA and DNA replication. We report the first immediate allergic hypersensitivity reaction to methylene blue-treated plasma transfusion....

Angiogenesis is the process of generating new blood vessels from preexisting vessels and is considered essential in many pathological conditions. The purpose of the present study was to evaluate the effect of methylene blue in chick chorioallantoic membrane angiogenesis model in vivo. In this well characterized model, methylene blue inhibited angiogenesis in a concentration-dependent manner. In...

The use of biodegradation methods by microorganisms in the removal of industrial dyes are widely considered owing to their high efficiency and compatibility to the environment. Therefore, this study aims to evaluate the biodegradation of methylene blue (MB) from aqueous solution by bacteria isolated from contaminated soil. This study was performed in laboratory scale on bacteria isolated and pu...