Intranuclear eosinophilic inclusion bodies were seen in the lactiferous duct and sinus epithelium of mammary tissues collected from a cow with clinical mastitis. Transmission electron microscopy revealed herpesvirus particles in these cells. Immunolabeling against anti bovine herpesvirus type 4 (BHV-4) rabbit serum was detected in nuclei that had intranuclear inclusion bodies. In addition, BHV-...

phalomyelitis Epizootica which had occurred in North China during the year 1940 . Pathologically, it was similar to the epizootic as seen in Japan from 1935 to 1938 , in which we found the intranuclear inclusion bodies , the so called •gJoest-Degen's Corpuscle•h, in the. nuclei of the ganglion cells and also cytoplasmic inclusion bodies , the so called •g Ichii's Corpuscle•h, in the protoplasma...

1. An epizootic disease of ferrets with a very high case fatality rate is described. 2. By the use of suitable material the natural disease can be transmitted experimentally. 3. The primary causative agent of the disease is a filterable virus. 4. Secondary invasion by bacteria of the respiratory tract of infected animals frequently occurs. The most important secondary invader is hemolytic strep...

The amount and distribution of intranuclear suggested the presence of intranuclear hehemoglobin in erythroblasts of normal submoglobin precipitation in some cells. jects and patients with homozygous Similar characteristic absorption peaks of thalassemia were studied by microspecdenatured ferric hemoglobin were recorded trophotometric methods. The mean intranuover large inclusions of the cytopla...

Polyomavirus nephropathy, also termed BK-virus nephropathy (BKN) after the main causative agent, the polyoma-BK-virus strain, is a significant complication after kidney transplantation. BKN is the most common viral infection that affects renal allografts with a prevalence of 1-9% on average 8-13 months post surgery. It can also occur sporadically in native kidneys. Viral nephropathy is caused b...

We give the first published description of the pathology and molecular findings associated with adenovirus infection in lizards in Australia. A central netted dragon (Ctenophorus nuchalis) exhibited severe necrotising hepatitis with abundant intranuclear inclusion bodies within hepatocytes and rarely within intestinal epithelial cells. Polymerase chain reaction (PCR) using pooled tissues yielde...

In a previous report (1), Pappenheimer and Enders described the occurrence of intranuclear inclusions in a large proportion of suckling mice with diarrhea (Fig. 1). The original stock in which the spontaneous disease had been prevalent for several years was virtually destroyed during the summer of 1945. Since then, new stock from several sources has developed spontaneous diarrhea, indistinguish...