PURPOSE Intravitreal injection of triamcinolone acetonide has been advocated to treat exudative diabetic macular edema. The purpose of the study was to evaluate the clinical outcome of an intravitreal injection of triamcinolone acetonide as treatment for diffuse diabetic macular edema. METHODS This study was a retrospective, interventional, clinical case series examining 210 eyes of 174 patie...

Purpose: To evaluate the influence of triamcinolone acetonide on the proliferation of retinal pigment epithelum cells in an experimental cell culture study. Methods: Pooled fresh porcine retinal pigment epithelium cell cultures were exposed to triamcinolone acetonide in increasing concentrations after the solvent agent had been removed. The proliferation rate was measured using the (3-(4,5-dime...

Aim: To evaluate the effect of intravitreal triamcinolone acetonide on the visual acuity of patients with exudative age related macular degeneration, to assess the duration of a possible effect, and to evaluate clinical side effects of the treatment. Methods: The study included 67 patients (71 eyes) who presented with exudative age related macular degeneration of predominantly or total occult t...

OBJECTIVES Recent reports of high endophthalmitis rates after intravitreal triamcinolone acetonide injection have raised concerns about the safety of this treatment. We sought to evaluate the effect of intravitreal triamcinolone injection on (1) the susceptibility to experimental bacterial endophthalmitis and (2) the subsequent therapeutic response to antibiotic treatment. DESIGN For the susc...

We report a case of a human leukocyte antigen B27 (HLA-B27)-negative patient with cystoid macular edema (CME) and ankylosing spondylitis (AS) after treatment with triamcinolone acetonide. The patient complained of deterioration of visual acuity of the right eye during the last 10 days. At presentation visual acuity of the right eye was 0.2, and the ophthalmic examination did not reveal any sign...

The purpose of this study is to follow up visual acuity in patients diagnosed with clinically significant macular edema and treated by an intravitreal injection of triamcinolone acetonide or in combination with bevacizumab. The working method: based on the selectivity criteria we involved 295 patients (460 eyes), divided into 2 groups according to the treatment administered and one control grou...

BACKGROUND Cystoid Macular Edema (CME) is one of the most common and sight threatening complications of uveitis. Intravitreal injection of corticosteroids and Anti-VEGF are two routine options for treatment. OBJECTIVE To compare the effects of intravitreal injections of Bevacizumab and Triamcinolone Acetonide for the treatment of persistent macular edema in non-infectious uveitis. METHODS I...

PURPOSE to report a case of severe ocular hypertension occurring as a complication after a single intravitreal injection of triamcinolone acetonide for the treatment of a diabetic cystoid macular edema. METHODS interventional case report. RESULTS a 63-year-old pseudophakic diabetic woman developed a severe and relatively sudden IOP increase to 50 mm Hg one month after receiving a single 4-m...

purpose : to evaluate the effectiveness of intravitreal triamcinolone acetonide on visual acuity and macular thickness using optical coherence tomography in macular edema associated with nonischemic central retinal vein occlusion (crvo). design : a prospective interventional case series. patients & methods : twenty eyes of 25 patients with nonischemic crvo and macular edema with visual acuity o...

Ophthalmic drug delivery to the posterior segment of eye has been challenging due complex ocular anatomy. Intravitreal injection drugs was introduced deliver therapeutic doses in segment. Different diseases including age-related macular degeneration, diabetic edema, retinal vein occlusions, uveitis, and cystoid among others, have historically treated with intravitreal corticosteroids injections...