Substituted 3,4-dihydro-1,8-naphthyridin-2(1H)-ones have been synthesized with the inverse electron-demand Diels-Alder reaction from 1,2,4-triazines bearing an acylamino group with a terminal alkyne side chain. Alkynes were first subjected to the Sonogashira cross-coupling reaction with aryl halides, the product of which then underwent an intramolecular inverse electron-demand Diels-Alder react...

There is currently a tremendous interest in developing bioorthogonal "click chemistry" methods for the modification of biopolymers. Very recently, inverse-electron-demand Diels-Alder reactions have received attention, but to date they have not been applied to nucleic acids. Here we describe the first example of DNA modification by inverse-electron-demand Diels-Alder reaction. We synthesized fou...

We consider a Cournot oligopoly model where multiple suppliers (oligopolists) compete by choosing quantities. We compare the aggregate profit achieved at a Cournot equilibrium to the maximum possible, which would be obtained if the suppliers were to collude. We establish a lower bound on the profit of Cournot equilibria in terms of a scalar parameter derived from the inverse demand function and...

This paper presents a novel approach to strictness analysis called abstract demand propagation, approach developed for the implementation of lazy functional programming languages on parallel machines. Although some work on strictness analysis using demand propagation has been done before, the present work is original in that it gives a precise interpretation of the notions of demands and demand...

To safeguard analytical tractability and the concavity of objective functions, the vast majority of models belonging to oligopoly theory relies on the restrictive assumption of linear demand functions. Here we lay out the analytical solution of a di erential Cournot game with hyperbolic inverse demand, where rms accumulate capacity over time à la Ramsey. The subgame perfect equilibrium is chara...