After viewing a film of a mother hitting her son, a film not seen by the college student interviewers, children were misinformed about a detail (via exposure to a misleading question) as well as explicitly coached to disclose 3 false details. The children were then interviewed by interviewers who had previously learned 1 of 3 different interviewing procedures: the Yuille Step-Wise Interview dev...

Tamoxifen (TAM), a non-steroidal antiestrogen, has revolutionized female breast cancer treatment. The mechanism involves is to compete with 17β-estradiol (E2) at the receptor site and blocking promotional role of E2 in cancer. Tam pioneering medicine because its widespread usage treatment chemoprevention, as well research into novel selective estrogen modulators (SERMs). In vast majority patien...

Chondral and osteochondral fractures of the lower extremities are important injuries because they can cause pain and dysfunction and often lead to osteoarthritis. These injuries can be misdiagnosed initially which may impact on the healing potential and result in poor long-term outcome. This comprehensive review focuses on current pitfalls in diagnosing acute osteochondral lesions, potential in...

Dry eye is a multifactorial, progressive, and chronic disease of the tears and ocular surface. The disease is multi-factorial and has intermittent symptoms. Discomfort, visual disturbance, tear film instability with potential damage to the ocular surface, and increased tear film osmolarity are known associates. Dry eye is a common clinical problem for eye-care providers worldwide and there is a...

Investigations involving digital media (e.g., hard disks and USB thumb drives) rely heavily on text string searches. Traditional search approaches utilizing matching algorithms or database technology and treebased indexing algorithms result in an overwhelming number of “hits” – a large percentage of which are irrelevant to investigative objectives. Furthermore, current approaches predominantly ...

We present a new robust signal for detecting deception: full body motion. Previous work on detecting deception from body movement has relied either on human judges or on specific gestures (such as fidgeting or gaze aversion) that are coded or rated by humans. The results are characterized by inconsistent and often contradictory findings, with smallstakes lies under lab conditions detected at ra...

Forty elderly psychiatric out-patients with an ICD-9 diagnosis of depression and twenty matched controls were studied for the presence of physical illnesses, using a pre-defined battery of investigative techniques. While the prevalence of physical illness diagnosis was not significantly different between the two groups, the number of subjects with undiagnosed illnesses and those with multiple i...

s scientists, we apply scientific investigative techniques to gain more understanding of what makes software “good” and how to make software well. Often, we adapt investigative techniques from other disciplines to define measures that make sense in the business, technical, and social contexts we use for decision making. However, sometimes we can learn as much from another discipline’s failures ...

Preservationists look to methods of nondestructive evaluation (NDE) to answer questions about the condition, strength, and construction details of wood in historic buildings in the interest of saving historic fabric and reducing or eliminating damage to significant historic features or materials caused by investigative probes. Many times, a basic wood inspection can answer questions posed when ...