a.sacharovi, which is one of the main malaria vectors of the palearchic region, is resistant to ddt in greece (1949), lebanon (1954), turkey (1959), syria and the u.s.s.r. (1972).the first record of a. sacharovi resistance to ddt in iran was given in 1959 from the kazeroon area, followed by izeh (1969) and meshkin-shahr (1970).this study (1973) urgently advises speedy measures to eliminate the ...

Background: The organochlorine DDT has estrogenic activity but the mechanism underlying the estrogenic activity of this pesticide remains unclear. In the present investigation here, we studied the transcriptional effects of a synthetic organochlorine pesticide o,p’-DDT [1.1.1.-trichloro-2-(o-chlorophenyl)-2-p-chloriphenyl ethane] and its metabolite p,p'-DDE (2-2-bis(4/chlorophenyl)-1-1-di...

Inhabitants of dwellings treated with DDT for indoor residual spraying show high DDT levels in blood and breast milk. This is of concern since mothers transfer lipid-soluble contaminants such as DDT via breastfeeding to their children. Focusing on DDT use in South Africa, we employ a pharmacokinetic model to estimate DDT levels in human lipid tissue over the lifetime of an individual to determi...

anopheles culicifacies is the vector of malaria in southeastern part of iran, india, west pakistan and ceylon. in 1959 the lc50 % ddt in the panchmahal district of gujarat state (india) had increased. ddt resistant population of a. culicifacies has been reported from west pakistan, burma and iran. after application of ddt in 1959, the density of a. culicifacies decreased sharply. the susceptibi...

One DDT-contaminated soil and two uncontaminated soils were used to enumerate DDT-resistant microbes (bacteria, actinomycetes and fungi) by using soil dilution agar plates in media either with 150 mg DDT ml−1 or without DDT at different temperatures (25, 37 and 55◦C). Microbial populations in this study were significantly (p<0.001) affected by DDT in the growth medium. However, the numbers of m...

BACKGROUND The debate regarding dichlorodiphenyltrichloroethane (DDT) in malaria prevention and human health is polarized and can be classified into three positions: anti-DDT, centrist-DDT, pro-DDT. OBJECTIVE We attempted to arrive at a synthesis by matching a series of questions on the use of DDT for indoor residual spraying (IRS) with literature and insights, and to identify options and opp...

BACKGROUND Previous studies of DDT and breast cancer assessed exposure later in life when the breast may not have been vulnerable, after most DDT had been eliminated, and after DDT had been banned. OBJECTIVES We investigated whether DDT exposure in young women during the period of peak DDT use predicts breast cancer. METHODS We conducted a prospective, nested case-control study with a media...

The biokinetics of p,p'-dichlorodiphenyltrichloroethane (DDT) and its metabolites, p,p'-dichlorodiphenydichloroethylene (DDE) and p,p'-dichlorodiphenyldichloroethane (DDD), in the green-lipped mussel Perna viridis were characterized in this study. We exposed the mussels to DDT in aqueous or dietary sources and then compared and evaluated the absorption, accumulation, distribution and eliminatio...