OBJECTIVE To determine serum level of the protease inhibitor, to identify phenotypes and determine their frequencies. STUDY DESIGN A prospective study. SETTING PMRC, Research Centre, JPMC and the Aga Khan University Hospital, Karachi. SUBJECTS Healthy adults without history of peptic ulcer disease and a normal endoscopy. METHODOLOGY Quantitative measurement of serum alpha 1 AT was carri...

Limited digestion of staphylococcal enterotoxin B (SEB) with trypsin resulted in the generation of a 12-Kda amino-terminal fragment and a 17-Kda carboxy-terminal fragment which were isolated by preparative iso-electric focusing. The carboxy-terminal fragment exhibited significant mitogenic activity for murine splenocytes, whereas the isolated amino-terminal fragment possessed little detectable ...

An electric field parallel to electrode arrays, which can be realized by switching DC electric fields, allows the electrophoretic levitation and focusing of negatively charged particles at the height of the anodes in the electrode arrays. Electric field calculations predict that charged particles will migrate parallel to the electrode array. The trajectories of particles well reflect the calcul...

Introduction: The basal brain activity and function rely on a constant supply of glucose in the brain tissue, which is regulated by glucose transportation through the blood-brain barrier (BBB) and the glucose consumption . Therefore, it is interesting to exploit in vivo approaches able to reliably measure the cerebral metabolic rate of glucose (CMRglc) and glucose transport constants (KT and Tm...

Two nanofiltration membranes, a Dow NF 270 polyamide thin film and a TriSep TS 80 polyamide thin film, were investigated for their retention of ionic species when filtering mine influenced water streams at a range of acidic pH values. The functional iso-electric point of the membranes, characterized by changes in retention over a small pH range, were examined by filtering solutions of sodium su...

This paper presents the first description of the motion subcorpus of ISO-SpaceBank (MotionBank) and discusses how motion-events are represented in ISO-Space 1.5, a specification language for the representation of spatial information in language. We present data from this subcorpus with examples from the pilot annotation, focusing specifically on the annotation of motion-events and their various...

ISO 26262 is an international standard for the functional safety of electric and electronic systems in vehicles, and this standard has become a major issue in the automotive industry. In this paper, a functional safety compliant electronic control unit (ECU) for an electric power steering (EPS) system and a demonstration purposed EPS system are developed, and a software and hardware structure f...

The increased activity in the field of Battery Electric Vehicles (BEVs) and Hybrid Electric Vehicles (HEVs) have led to an increase in standardization work, performed by both world-wide organizations like the IEC or the ISO, as by regional and national bodies such as CEN, CENELEC, SAE or JEVA. The issues of these standards cover several topics: safety, performance and operational/dimension issu...