low molecular weight heparin-modified isoliquiritigenin-loaded solid lipid nanoparticle (lmwh-isl-sln) was developed for injective application. the morphological observation, particle diameter and zeta potential of lmwh-isl-sln were characterized using transmission electron microscopy (tem) and a malvern zetasizer. its entrapment efficiency (ee) and drug loading (dl) were determined by ultracen...

The utilization of natural compounds as therapeutic agents to treat pancreatic cancer has recently focused on drug research. Calotropis gigantea long been believed be a medicinal plant that helps in treating various diseases. bioactive 9-metoxipinoresinol and isoliquiritigenin isolated from C. leaves are proven act by inhibiting the cell growth Panc-1 cells. This study aimed screen potential mo...

The 5-deoxyisoflavones, afrormosin and formononetin have been isolated from healthy leaves of Onobrychis viciifolia. In addition to these compounds, several other flavonoid (isoliquiritigenin; liquiritigenin; garbanzol) and isoflavonoid (medicarpin; vestitol) derivatives including the new isoflavanone, vestitone (7,2'-dihydroxy-4'-methoxyisoflavanone), are present in leaves inoculated with the ...

Introduction: Astragalus membranaceus Fisch. ex Bunge is a traditional botanical drug with antibacterial, antioxidant, antiviral, and other biological activities. In the process of industrialization A. , most aboveground stems leaves are discarded without resource utilization except for small amount low-value applications such as composting. This study explored antibacterial activity stem leaf ...

Yellow color in dahlia flowers is conferred from chalcones, butein and isoliquiritigenin. The intensity of yellow cultivars diverse, but a detailed study on this has not yet been performed. In study, we first identified structures flavonoids by nuclear magnetic resonance imaging ray florets the red-white bicolor ‘Shukuhai’, which contains flavones anthocyanins. Four anthocyanins, four flavone d...

Isoliquiritigenin (ISL), a natural antioxidant, has antitumor activity in different types of cancer cells. However the antitumor effect of ISL on human tongue squamous carcinoma cells (TSCC) is not clear. Here we aimed to investigate the effects of synthetic isoliquiritigenin (S-ISL) on TSCC and elucidate the underlying mechanisms. S-ISL was synthesized and elucidated from its nuclear magnetic ...