The metabolism, both in vitro and in vivo, of the chiral isomers of the phosphonodithioate insecticide fonofos was examined. The absolute configurations of the fonofos isomers and relevant oxidation products were established by x—ray diffraction analysis and chemical correlation. Oxidation of fonofos to the corres— ponding oxon in the presence of mouse liver mixed—function oxidase occurred pred...

Sn-BEA zeolite is known to catalyze the aldose-to-ketose isomerization of xylose and glucose; however, the selectivity to pentose and hexose isomers is not stoichiometric, suggesting the formation of other products. In the present study, we have observed near-complete conversion of all pentose and hexose isomers when xylose and glucose were reacted in the presence of Sn-BEA at 140 8C and 200 8C...

Energetically highly disfavored geometric isomers are present in only trace amounts in solution and hence cannot be clearly observed by conventional spectroscopic methods. Here, we provide spectroscopic evidence that a suitably sized/shaped cavitand (alpha-cyclodextrin) can discriminate distinctive stereochemical differences between all possible cis-trans stereoisomers of a qualified compound, ...

Naphthol is a widely used chemical and medical detection biomarker, but it harmful to human health the environment. Therefore, highly sensitive method for naphthol urgently required. Herein, an electrochemical microsensor simultaneous of isomers was fabricated by in situ growth three-dimensional graphene network (3DGN) on screen-printed electrodes. The exhibited good sensing responses typical (...

Chemical separation has great importance in industrial applications. Separation of xylene isomers still prevails to be one of the most important challenges in chemical industry, due to the large amount of commercial use of p-xylene in the production of beverage bottles, fibers and films. A novel Zn(II)-based dynamic coordination framework based on flexible ether-linkage, exhibiting selective ad...

One limitation in the growing field of ambient or direct analysis methods is reduced selectivity caused by the elimination of chromatographic separations prior to mass spectrometric analysis. We explored the use of high-field asymmetric waveform ion mobility spectrometry (FAIMS), an ambient pressure ion mobility technique, to separate the closely related opiate isomers of morphine, hydromorphon...

Although acetylenic acids are not normally found in mammalian tissues, octadecynoyl-CoA esters can serve as substrates for rat liver microsomal acyl-CoA: phospholipid acyltransferases. The relatively high rate of transfer to the 2-hydroxyl of I-acylglycerol-3-phosphorylcholine by the 5-, 9-, and I2-positional cis, tram and yne isomers of acids supports the concept that n-bonds at these position...

Activity-based protein profiling has emerged as a powerful tool for visualizing glycosidases in complex biological samples. Several configurational cyclophellitol isomers have been shown to display high selectivity as probes for glycosidases processing substrates featuring the same configuration. Here, a set of deoxygenated cyclophellitols are presented which enable inter-class profiling of β-g...

A new strategy for the design of a new chromatographic stationary phase via simple modifications of the counter anions in poly(ionic liquid)-grafted silica phase based on ionic self-assembly technology is proposed. The phase with methyl orange dye as counter anions exhibits ultra-high selectivity towards shape-constrained isomers.