To determine whether thymidine kinase (TK) isozyme status adds clinically useful information in adult nonHodgkin’s lymphoma (NHL). we have analyzed peripheral blood plasma and lymphocytes of 44 patients with NHL for either TK1 or TK2 isozyme activity. On the basis of isozyme status. patients could be divided into two groups that did not differ significantly with respect to known determinants fo...

Two isozymes of glutamate dehydrogenase were shown to exist in a thermophilic strain of Chlorella pyrenoidosa. The NADPH:NADH activity ratios of the NADHand NADPHspecific isozymes were 1: 5 and 33: 1, and the molecular weights were estimated to be 179,000 and 269,000, respectively. Only the NADH-specific isozyme was detectable in nitrate-cultured cells; the synthesis of the NADPH-specific isozy...

Isozyme 4 of rabbit liver microsomal cytochrome P-450 was shown earlier in this laboratory to contain multiple NH2-terminal residues, whereas isozymes 2, 3a, 3b, and 3c have single, unique NH2-terminal sequences. Similar results were obtained with isozyme 4 obtained from animals that were untreated, treated with phenobarbital (which does not induce this isozyme), or induced with beta-naphthofla...

In a recent study on Gulf War veterans who developed delayed neurotoxicity symptoms, we found their levels of serum paraoxonase (PON1) isozyme type Q to be significantly lower than in the control, unaffected veteran group. These results were obtained 25 ill and 20 well control subjects, which 10 deployed nondeployed battalion members remained United States during War. The blood samples also ass...

Protein kinase C (PKC) isozymes comprise a family of related enzymes. There are only limited differences between these isozymes in substrate specificity or sensitivity to activators. However, there are multiple isozymes within a cell mediating isozyme-specific functions. Differential subcellular localization has been proposed to explain this specificity. When members of the PKC family are activ...

Following blastocyst implantation, or outgrowth in vitro, the LDH isozyme pattern changes from that of the maternally inherited B subunit isozyme form (LDH-1) to a pattern dominated by A subunits (Auerbach & Brinster, 1967, 1968). In preimplantation embryos we have observed additional isozyme bands, as yet unidentified. An analysis of the pattern of newly synthesized LDH isozymes and specific a...

in order to evaluate salt (nacl) tolerance in alfalfa (medicago sativa l.) half-sib families, a factorial experiment on the basis of completely randomized design, with 20-25 individuals in pot (replicates) was carried out under field conditions at the research station of university of tabriz. electrophoretic analyses were performed by using 7.5% slab polyacrylamide gels. two antioxidant enzymes...

The present study was aimed at the development of a somoclonal variant and isozyme marker for Phyllanthus amarus Schum & Thonn using inter-nodal segments and the enzyme peroxidase. Maximum callus proliferation was obtained on Murashige and Skoog’s medium supplemented (MS) with 1.0 mg/l of 2,4-Dichlorophenoxyacetic acid. Three weeks-old pale yellowish white semi-friable callus was used for organ...