نتایج جستجو برای: jacob disease
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Sporadic Creutzfeldt-Jacob disease (sCJD) usually presents with typical clinical signs. Prodromal symptoms lasting for several weeks are followed by dementia, myoclonus, ataxia and abnormalities of vision (1). Supranuclear gaze palsies accompanying sCJD have rarely been reported. Some of these reported cases were initially diagnosed as progressive supranuclear palsy (PSP) and the diagnosis was ...
Sporadic Creutzfeldt-Jacob disease (CJD) is a rare fatal neurodegenerative prion disease. Clinical fi ndings of CJD consist of a rapid onset dementia, myoclonus, and neurologic disorders. Defi nitive diagnosis is established with histopathologic confi rmation of brain parenchyma or autopsy materials. Periodic triphasic electroencephalography (EEG) changes and detection of 14-3-3 protein in cere...
In his essay "Evolution and Tinkering," published in Science in 1977, François Jacob argues that a common analogy between the process of evolution [4] by natural selection [5] and the methods of engineering is problematic. Instead, he proposes to describe the process of evolution [4] with the concept of bricolage (tinkering). In this essay, Jacob does not deny the importance of the mechanism of...
BACKGROUND An 81 year old female presented with altered mental status after new onset of severe depression and suicidal ideation with recent psychiatric hospitalization. CASE PRESENTATION Key clinical features included muscle rigidity, prominent startle reflex, and rapidly progressing cognitive decline. Initial working hypothesis was serotonin syndrome or neuroleptic malignant syndrome but co...
Uzma Ansari, Centers for Disease Control and Prevention Adrian Lawsin, Centers for Disease Control and Prevention Davina Campbell, Centers for Disease Control and Prevention Valerie Albrecht, Centers for Disease Control and Prevention Gillian McAllister, Centers for Disease Control and Prevention Sandra Bulens, Centers for Disease Control and Prevention Maroya Spalding Walters, Centers for Dise...
How is what an agent ought to do related to what an agent ought to prefer that she does? More precisely, suppose we know what an agent’s preference ordering ought to be over the outcomes of performing the various courses of action open to her. Can we infer from this information how she ought to act, and if so, how can we infer it? One view (which, for convenience, I will call ‘actualism’) is th...
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