BACKGROUND The processes of leukemogenesis and differentiation of the megakaryo-erythroid lineage remain poorly understood. Leukemic cell lines derived from megakaryocytic leukemia are valuable reagents for studies on these events. MATERIALS AND METHODS A new cell line, JAS-R, was established from a 64-year-old patient with acute megakaryocytic leukemia (AML M7). Its characteristics were stud...

Host cell entry by Toxoplasma gondii depends critically on actin filaments in the parasite, yet paradoxically, its actin is almost exclusively monomeric. In contrast to the absence of stable filaments in conventional samples, rapid-freeze electron microscopy revealed that actin filaments were formed beneath the plasma membrane of gliding parasites. To investigate the role of actin filaments in ...

In this letter, we show that Fan-Chen-Yeh’s blind signature scheme and Chien-Jan-Tseng’s partially blind signature scheme are vulnerable to the chosen–plaintext attack. We also show that both schemes can be modified so that the chosen– plaintext attack is impossible. But, still Chien-Jan-Tseng’s partially blind signature scheme is vulnerable. It fails to satisfy the partial blindness property. ...

We propose JAS, a JVM-based active storage framework for object-based storage systems. JAS programs the active storage functions of users as Java codes, and allows them to be executed on different OSD platforms (Operating systems and hardware) without recompiling. JAS offloads the active storage code from a client to the OSD by extending the standard OSD command set, and execute the Java code o...

Background: Antipsychotics are commonly prescribed for a variety of psychiatric disorders which require prolonged treatment. If costly brand is prescribed, it reduces patient compliance, especially in the lower socio-economic groups. Awareness about cost variation among different brands will guide an economically effective prescription by treating physician.Methods: The used oral antipsychotic ...

Background: The price of medicine in India has always been a point discussion public domain. range the same drug is very large with more than 100% difference between various brands available different settings. Aims and Objectives: To assess drugs at Jan Aushasdhi (JA), AMRIT Private Chemist to compare prices these three outlets so that issues. Material Methods: This institution-based cross-sec...

Cloud computing has become increasingly popular model for delivering applications hosted in large data centers as subscription oriented services. Hadoop is a popular system supporting the MapReduce function, which plays a crucial role in cloud computing. The resources required for executing jobs in a large data center vary according to the job type. In Hadoop, jobs are scheduled by default on a...

Enterprise engineering originated as a practice with most publications focusing on the practical facets without the underlying scientific foundation. Foundational works emerged from different authors in recent years, including Dietz, Hoogervorst and Giachetti. According to Gregor, the bodies of knowledge or theories encompassed in a discipline need to address questions related to four classes n...

BACKGROUND Butanol as an important chemical and potential fuel could be produced via ABE fermentation from lignocellulosic biomass. The use of food-related feedstocks such as maize and sugar cane may not be a sustainable solution to world's energy needs. Recently, Jerusalem artichoke tubers containing inulin have been used as feedstock for butanol production, but this bioprocess is not commerci...