Juvenile xanthogranuloma is a relatively rare cutaneous tumor of histiocytic origin, occurring mainly in neonates, children, and young people in the first 2 decades of life. An occurrence in adults is rare. Very rare is also a "deep" subcutaneous and intramuscular localization of this tumor that is called in such case as "deep juvenile xanthogranuloma." A very uncommon variant of this tumor is ...

Five infants with biopsy proved juvenile xanthogranuloma of the iris were reviewed. Early treatment with subconjunctival injection of steroids and topical steroid drops resulted in regression of the lesion in four patients. One patient, reviewed at the age of 8 months after glaucoma which had developed secondary to the iris xanthogranuloma, had been treated by surgery alone: the visual outcome ...

Juvenile xanthogranuloma is a rare disorder which may be present at birth, or appears in infancy. It can also occur in adults of all ages, appears with lesions that may be solitary or multiple nodules several millimeters in diameter. The predilection sites are head and neck, but it may occur on the extremities and trunk also. Internal organs such as lung, kidney, gastrointestinal tract etc. can...

Five infants with biopsy proved juvenile xanthogranuloma of the iris were reviewed. Early treatment with subconjunctival injection ofsteroids and topical steroid drops resulted in regression of the lesion in four patients. One patient, reviewed at the age of 8 months after glaucoma which had developed secondary to the iris xanthogranuloma, had been treated by surgery alone: the visual outcome w...

© 2014 The Authors. doi: 10.2340/00015555-1712 Journal Compilation © 2014 Acta Dermato-Venereologica. ISSN 0001-5555 Juvenile xanthogranuloma (JXG) is a non-Langerhans histiocytosis occurring predominantly in infancy and early childhood. Resolution usually occurs over a period of months to several years, and it is rare for the condition to persist beyond late childhood (1). The symmetrical gian...

Juvenile xanthogranuloma of the iris has only twice before been reported as occurring bilaterally. In this present bilateral case, treatment with steroids and irradiation was sucessful in eradicating the lesion from the lesser affected eye.

Palmer and Bowling [1] have recently described the dermoscopic features in 3 cases of juvenile xanthogranuloma (JXG). A dermoscopic pattern characterized by orange-yellow background with ‘clouds’ of paler yellow deposits was observed in all patients. We have had recent occasion to observe many cases of single and multiple JXG and noted a further constant dermoscopic feature, namely branched and...