In the present study, we investigated the effect of Ginkgo biloba extracts and some of its individual constituents on the catalytic activity of human cytochrome P450 enzymes CYP1B1, CYP1A1, and CYP1A2. G. biloba extract of known abundance of terpene trilactones and flavonol glycosides inhibited 7-ethoxyresorufin O-dealkylation catalyzed by human recombinant CYP1B1, CYP1A1, and CYP1A2, and human...

The chromatographic fractionation of the Mauritia flexuosa L. f., Arecaceae, leaves extract, a plant known by the name of buriti palm tree, resulted in the isolation of six flavonoids: tricin-7-O-rutinoside, apigenin-6-C-arabinoside, 8-Cglucoside (isoschaftoside), kaempferol-3-O-rutinoside (nicotiflorine), quercetin-3O-rutinoside (rutin), luteolin-8-C-glucoside (orientin) and luteolin-6-C-gluco...

Microctis Folium, the leaves of Microcos paniculata L., is a commonly used herbal tea material. The methanol extract of Microctis Folium and its principle compounds vitexin (1), isovitexin (2) and isorhamnetin 3-O-β-D-rutinoside (3) were investigated for their α-glucosidase inhibitory effects. The extract showed strong α-glucosidase inhibitory effect (IC₅₀ = 61.30 μg/mL) and the three flavonoid...

Two new prenylated flavonoids, named scariosin (1) and isorhynchospermin (2) were isolated from the leaves of paracalyx scariosa together with kaempferol, quercetin, kaempferol 3-O- rutinoside and rutin. The structures of (1) and (2) were characterized as 8-C- prenyl- taxifolin 7,3'-dimethylether and 6-C-prenylquercetin 7,4'-dimethylether by their chemical and spectra data, respectively.

An experimental setup based on a 2(3) full-factorial, central-composite design was implemented with the aim of optimising the recovery of polyphenols from olive leaves by employing reusable and nontoxic solutions composed of water/ethanol/citric acid as extracting media. The factors considered were (i) the pH of the medium, (ii) the extraction time and (iii) the ethanol concentration. The model...

Four known flavonoids: quercetin 3-O-β-D-rutinoside (Q3Rut), myricetin 3-O-β-D-galactopyranoside (M3Gal), quercetin 3-O-β-D-galactopyranoside (Q3Gal) and quercetin 3-O-β-D-glucopyranoside (Q3Glc), for the first time were isolated from aerial parts of Euphorbia microsciadia. The chemical structure of them was elucidated on the basis of 1 and 2 D-NMR spectra and different spectroscopic techniques...

Blueberries are particularly rich in anthocyanins and favored extensively for their health benefits. In this study, the anthocyanin profiles of fruits four blueberry cultivars (Gardenblue, Legacy, Misty, Brightwell) were investigated. Total content gradually increased all during development, but mature Brightwell Gardenblue had a higher than those Legacy Misty. Thirty-two kinds quantified using...

From leaves of Triticum aestivum a new O-glycosylflavone has been isolated together with chlorogenic acid and its 3'-methyl ether and 6 C-glycosylflavones. The structure of the new flavonoid was determined by 1D and 2D NMR techniques and other spectral evidence as 5,7-dihydroxy-3',4',5'-trimethoxyflavone-7-O-beta-rutinoside.

The inhibitory activity on pancreatic α-amylase by cyanidin-3-rutinoside was examined in vitro. The IC₅₀ value of cyanidin-3-rutinoside against pancreatic α-amylase was 24.4 ± 0.1 μM. The kinetic analysis revealed that pancreatic α-amylase was inhibited by cyanidin-3-rutinoside in a non-competitive manner. The additive inhibition of a combination of cyanidin-3-rutinoside with acarbose against p...