Introduction: Odontogenic cysts are characterized by an expansile non–infiltrative growth through several mechanisms which include presence of mast cells in the capsule. The mast cells can be demonstrated histochemically as well as immunohistochemically. Aim and Objectives: The primary objective of the study was to analyze the presence and distribution of mast cells in radicular cyst, dentigero...

BACKGROUND The aims of this study were to investigate the immunolocalization of ezrin and its relationship with the podoplanin expression in keratocystic odontogenic tumors. MATERIAL AND METHODS The immunohistochemical expressions of ezrin and podoplanin by odontogenic epithelium were evaluated in keratocystic odontogenic tumors using monoclonal antibodies. RESULTS Our results showed strong...

BACKGROUND AND PURPOSE Ameloblastomas and keratocystic odontogenic tumors are major aggressive odontogenic tumors in the maxillomandibular regions, but the differentiation between these 2 tumors is frequently ineffective based on only conventional CT and MR imaging findings. Here, we evaluated diffusion-weighted MR imaging for the differentiation of these 2 odontogenic tumors. MATERIALS AND M...

OBJECTIVE In jawbones, ameloblastomas and odontogenic keratocysts share many clinical features in common such as aggressiveness, high recurrence rates and radical management options. Understanding the pathogenesis and biological aspects of these tumors would improve the success of diagnose and treatment procedures. The aim of this study was to exhibit the reasons of high recurrence rates and gr...

BACKGROUND The keratocystic odontogenic tumor (KCOT) is a relatively rare, benign neoplasm which develops in the maxilla or mandible, arising from the dental lamina or basal cells of the oral epithelium. It is often found incidentally and brings about late symptoms as it does not cause bone distension for a long time. CASE REPORT The presented case is of a young woman with a giant keratocysti...

Calcifications or hard tissue deposits in the wall of keratocystic odontogenic tumor (KCOT) are rare and uncommon. Three types of calcifications have been reported in the literature: dystrophic, cartilagenous, dentinoid. A case of maxillary KCOT with calcification is reported with a review on prevalence and pathogenesis of these calcifications. The calcifications associated with the connective ...

Introduction: A keratocystic odontogenic tumor is a benign intra-bone mass originating from dental lamina or its residue. It represents 2–11% of jaw cysts, and has a slow but aggressive growth. The evaluation of molecular characteristics, immunohistochemistry, and genetic expression currently have no established classification regarding the evolution and pathophysiologic pattern of these lesion...

Inclusion bodies are nuclear or cytoplasmic aggregates of proteins that may be formed due to infections or genetic disorders. Asteroid body is one such inclusion that is eosinophilic and spider like that are usually found in infections like sarcoidosis and sporotrichosis. Inclusions are usually pathognomonic of certain diseases and conditions, navigating the pathologist to arrive at a diagnosis...

keratocystic odontogenic tumor (kcot) is a benign intraosseous neoplasm of the jaw occurring most commonly in mandibular ramus molar area with male predilection. peripheral kcots are very uncommon. here we report a case of keratocyst in buccal mucosa in a 55 years old female patient, the diagnosis of which was based on subjective histological evaluation and further confirmed by immunohistochemi...