Kernicterus, a preventable brain injury resulting from severe neonatal jaundice, has reemerged in the US (1–3). Newborn jaundice, a usually benign condition that typically resolves with supervision and appropriate nutritional intake, can progress to severe hyperbilirubinemia in 8–10% of healthy newborn infants. Severe hyperbilirubinemia may need treatment with phototherapy. Some newborns discha...

Despite efforts to eliminate permanent and irreversible brain damage due to bilirubin encephalopathy and kernicterus, these conditions continue to accompany us into the third millennium. This phenomenon occurs not only in developing countries with emerging medical systems, but in Westernized countries as well. Comprehensive guidelines to detect newborns with jaundice and treat those in whom hyp...

For many years, to reduce the crash frequency and severity at high-speed signalized intersections, warning flashers have been used to alert drivers of potential traffic-signal changes. Recently, more aggressive countermeasures at such intersections include a speed-limit reduction in addition to warning flashers. While such speed-control strategies have the potential to further improve the crash...

prevention of extreme neonatal hyperbilirubinemia in a mature health maintenance organization. Arch Pediatr Adolesc Med. 2000;154:1140-7. 11. Manning DJ, Maxwell MJ, Todd PJ, Platt MJ. Prospective surveillance study of severe hyperbilirubinaemia in the newborn in the United Kingdom and Ireland. Arch Dis Child Fetal Neonatal Ed. 2006; [Epub ahead of print]. http://fn.bmj.com/cgi/rapidpdf/adc.200...

Neonatal jaundice [2] is the yellow discoloration of the skin and eyes due to elevated bilirubin levels in the bloodstream of a newborn. Bilirubin is a byproduct of the breakdown of red blood cells. Jaundiced infants are unable to process bilirubin at a normal rate or they have an abnormally high amount of bilirubin in their bloodstream, resulting in a buildup of the yellow colored bilirubin. T...