نتایج جستجو برای: lactic

تعداد نتایج: 49766  

Journal: :Journal of nutritional science and vitaminology 1981
M Morotomi K Sakai K Yazawa N Suegara Y Kawai M Mutai

We investigated the effect and the fate of an extremely high amount of orally administered lactic acid in rats. The dosed amount of lactic acid, 390 mg per 200 g body weight (30 times higher than that normally detected in the stomach of rats), was determined from the results of observation of acute toxicity of lactic acid in rats. Six hours after the administration of excess lactic acid togethe...

2017
Caili Zhang Cheng Zhou Nilnate Assavasirijinda Bo Yu Limin Wang Yanhe Ma

BACKGROUND Optically pure D-lactic acid (≥ 99%) is an important precursor of polylactic acid. However, there are relatively few studies on D-lactic acid fermentation compared with the extensive investigation of L-lactic acid production. Most lactic acid producers are mesophilic organisms. Optically pure D-lactic acid produced at high temperature not only could reduce the costs of sterilization ...

Journal: :iranian journal of veterinary research 2009
p. azadnia a. h. khan nazer

morphological, cultural, physiological and biochemical characteristics were employed to identify lactic acid bacteria (lab), isolated from drinking yoghurt in different areas in fars province, iran. from 18 drinking yoghurt samples a total of 673 lab positives were determined, in which 117 (17.38%) and 556 (82.62%) were identified as lactic acid cocci and lactic acid bacilli, respectively. addi...

Journal: :Blood 2007
Karin Fischer Petra Hoffmann Simon Voelkl Norbert Meidenbauer Julia Ammer Matthias Edinger Eva Gottfried Sabine Schwarz Gregor Rothe Sabine Hoves Kathrin Renner Birgit Timischl Andreas Mackensen Leoni Kunz-Schughart Reinhard Andreesen Stefan W Krause Marina Kreutz

A characteristic feature of tumors is high production of lactic acid due to enhanced glycolysis. Here, we show a positive correlation between lactate serum levels and tumor burden in cancer patients and examine the influence of lactic acid on immune functions in vitro. Lactic acid suppressed the proliferation and cytokine production of human cytotoxic T lymphocytes (CTLs) up to 95% and led to a...

2016
Lawrence P. Wackett

An annotated selection of World Wide Web sites relevant to the topics in microbial biotechnology Lactobacillales (lactic acid bacteria):Wikipedia This page on the lactic acid group of bacteria is heavy on taxonomy. This webpage describes the major taxonomic and metabolic features of lactic acid bacteria. Twelve reasons to know about lactic acid bacteria Lactic acid bacteria are important in foo...

2014
Lili Peng Nengzhong Xie Ling Guo Limin Wang Bo Yu Yanhe Ma

Lactic acid is one of the top 30 potential building-block chemicals from biomass, of which the most extensive use is in the polymerization of lactic acid to poly-lactic-acid (PLA). To reduce the cost of PLA, the search for cheap raw materials and low-cost process for lactic acid production is highly desired. In this study, the final titer of produced L-lactic acid reached a concentration of 185...

بینش, فریبا, فلاح, راضیه, مرتضوی زاده, محمد رضا,

Mitochondrial myopathy, lactic acidosis, and siderobastic anemia (MLA SA) syndrome is one of the newly reported mitochondrial diseases, seven cases of which have been reported. We report a child with inflammatory myopathy, sideroblastic anemia and lactic acidosis .The patient is a 8.5 year old boy with normal cognitive function suffering from chronic progressive weakness in lower extremities, ...

Journal: :Drug metabolism and pharmacokinetics 2004
Masaki Kobayashi Shirou Itagaki Takeshi Hirano Ken Iseki

L-lactic acid transport plays an important role in the regulation of L-lactic acid circulation into and out of muscle. To clarify the transport mechanism of L-lactic acid in skeletal muscle, L-lactic acid uptake was investigated using a L6 cell line. mRNAs of monocarboxylate transporter (MCT) 1, 2 and 4 were found to be expressed in L6 cells. The [(14)C] L-lactic acid uptake by L6 cells increas...

Journal: :PLoS ONE 2009
Jiayang Qin Bo Zhao Xiuwen Wang Limin Wang Bo Yu Yanhe Ma Cuiqing Ma Hongzhi Tang Jibin Sun Ping Xu

BACKGROUND The demand for lactic acid has been increasing considerably because of its use as a monomer for the synthesis of polylactic acid (PLA), which is a promising and environment-friendly alternative to plastics derived from petrochemicals. Optically pure L-lactic acid is essential for polymerization of PLA. The high fermentation cost of L-lactic acid is another limitation for PLA polymers...

2017
Toshimitsu Ohashi Mitsuhiro Aoki Hiroyuki Tomita Takashi Akazawa Katsuya Sato Bunya Kuze Keisuke Mizuta Akira Hara Hitoshi Nagaoka Norimitsu Inoue Yatsuji Ito

Reprogramming of glucose metabolism in tumor cells is referred to as the Warburg effect and results in increased lactic acid secretion into the tumor microenvironment. We have previously shown that lactic acid has important roles as a pro-inflammatory and immunosuppressive mediator and promotes tumor progression. In this study, we examined the relationship between the lactic acid concentration ...

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