Despite their immunosuppressive effects, corticosteroids have long been used as adjunct therapy (aCST) in the treatment of infectious diseases. The rationale is that in certain infections it is necessary to decrease the exacerbated host's inflammatory response, which can otherwise result in tissue damage and organ dysfunction. In fact, a major concern in treating paracoccidioidomycosis (PCM) is...

OBJECTIVE To evaluate outcomes of balloon dilation laryngoplasty for laryngeal stenosis in children. DESIGN Retrospective study. SETTING Academic tertiary care department of pediatric otolaryngology. PATIENTS All children treated with laryngeal balloon dilation (primarily or secondarily following laryngeal surgery) from 2002 to 2010. MAIN OUTCOME MEASURES Stenosis severity, measured usi...

INTRODUCTION Balloon dilatation is a method of choice for treatment of laryngeal stenosis in children. The aim of procedure in apneic pause is to avoid new insertion of tracheostomy cannula. PATIENTS AND METHODS The authors performed balloon dilatation of subglottic laryngeal strictures (SGS) in 5 children (3 girls and 2 boys) without tracheotomy. Two of them with traumatic and inflammatory S...

BACKGROUND Laryngotracheal stenosis (LTS) can be either congenital or acquired. Laryngeal stenosis is most often encountered after prolonged intubation. The mechanism for stenosis following intubation is believed to be hypertrophic scarring. Mesenchymal stem cells (MSCs) therapy has shown promising results in regenerative medicine. We aimed to systematically review the literature on MSC therapy...

BACKGROUND Osteoradionecrosis (ORN) of the hyoid bone sometimes induces severe front neck infection and can cause laryngeal stenosis and carotid rupture. Although ORN of the hyoid bone is known to be a complication of chemoradiotherapy for head and neck cancer, there has been no basis for its evaluation. Our purpose is to present the clinical and MR imaging features of ORN of the hyoid bone. ...

OBJECTIVES/HYPOTHESIS This study aimed to report our experience in the management of congenital laryngeal stenosis and to compare our series and results to published data in the literature. STUDY DESIGN Retrospective case series. Tertiary referral center for rare pediatric head and neck malformations. METHODS Medical charts of patients diagnosed with congenital laryngeal stenosis in our ins...

OBJECTIVE Laryngeal reconstruction is needed to preserve laryngeal function in patients who have undergone extensive vertical or frontal partial laryngectomy. However, the procedure remains a difficult challenge. Several reconstruction techniques have been described, but these techniques pose risks of complications such as laryngeal stenosis. This study aimed to evaluate the postoperative cours...

INTRODUCTION The Montgomery silicone tracheal T-tube (Safe-TTube) has gained a role in laryngeal and tracheal reconstruction and revision by providing patients a longterm, indwelling stent that allows voice production and swallowing. Montgomery designed the tracheal T-tube in 1968.l The T-tube is made of silicone and therefore relatively inert and resistant to tissue reaction.2 It can be used f...

OBJECTIVES/HYPOTHESIS The aim of this study was to systematically review available literature on the outcomes of children treated with balloon laryngoplasty (BLP) as a primary or adjuvant treatment for subglottic or laryngeal stenosis, as well as briefly report on a new series of 60 children treated at the Medical University of South Carolina from 2007 to 2013. STUDY DESIGN Review of publishe...

INTRODUCTION Laryngeal stenosis has various causes and treatment options. Endoscopic resection of the stenotic part with CO2 laser is one of the treatment options of laryngotracheal stenosis. Keels are useful for preventing adhesion formation, restenosis and web formation, which may happen during the later stage. They can be put in place either via the endoscopic approach or through a micro thy...