INTRODUCTION There is a paucity of data on the occurrence of congenital toxoplasmosis in children born to mothers dually infected with HIV and Toxoplasma gondii. OBJECTIVE To evaluate aspects of the mother-infant pairs associated with vertical transmission of toxoplasmosis in women co-infected with HIV in a referral center for perinatally acquired infections in Belo Horizonte, Brazil. METHO...

BACKGROUND About 30% of the population worldwide are infected with the protozoan parasite Toxoplasma gondii. Latent toxoplasmosis has many specific behavioral and physiological effects on the human organism. Modified reactivity of the immune system has been suggested to play a key role in many of these effects. For example, the immunosuppression hypothesis explains the higher probability of the...

Toxoplasma gondii is a worldwide protozoan parasite that infects almost all warm-blooded animals. Although human toxoplasmosis mostly latent, pregnant women and immunocompromised patients need effective treatment. There are drugs of choice for treatment toxoplasmosis; however, due to their side effects and/or disease stage-specificity, prescription them limited. During recent years, nanomedicin...

Toxoplasmosis is an important parasitic disease in immunosuppressed patients. This prospective study was conducted to determine the seroprevalence, associated risk factors and the incidence of clinically confirmed toxoplasmosis among renal patients at the University of Malaya Medical Center, Kuala Lumpur, Malaysia. We interviewed 247 renal patients, each of whom answered an epidemiological ques...

The aim of this study was to test the potential diagnostic usefulness of recombinant Toxoplasma gondii rhoptry antigens, ROP2 and ROP4, with respect to toxoplasmosis detection and infection phase distinction in laboratory mouce by determining specific serum IgM and IgG antibodies with the use of indirect ELISA technique. The mice antibody response to ROP antigens was significantly higher in the...

Hospital Physician July 2008 17 T oxoplasma gondii is an obligatory intracellular pathogen that infects a large proportion of the world population and is a well-recognized cause of illness among persons with AIDS.1 T. gondii infection typically is latent and remains asymptomatic in both immunocompetent individuals and HIV-infected patients. However, patients with HIV are at risk for developing ...

Latent toxoplasmosis is probably the most common protistan parasitic disease with many indirect negative impacts on human health. One of the important impacts is impaired psychomotor function leading to reduced driving efficiency in Toxoplasma-seropositive subjects. Numerous case-control studies have established a positive relation between the seroprevalence of Toxoplasma gondii (Nicolle et Man...

In this paper, we construct a more realistic mathematical model to study toxoplasmosis dynamics. The considers two discrete time delays. first delay is related the latent phase, which lag between when susceptible cat has effective contact with an oocyst and it begins produce oocysts. second that elapses from oocysts become present in environment they are able infect. main aim paper find conditi...

OBJECTIVES Toxoplasma gondii, a parasitic protozoan, infects about 30 - 60% of people worldwide. Toxoplasma is known to induce behavioral changes and an increase of dopamine in mice. The presence of anti-Toxoplasma antibodies (latent toxoplasmosis) is also a risk factor for schizophrenia. Latent toxoplasmosis in men (male soldiers) is associated with lower novelty seeking. As the novelty seekin...