Objective(s): In this study, we investigated the protective effects of piperine on lead acetate-induced renal damage in rat kidney tissue. Materials and Methods: Forty male rats were divided into 5 groups: negative control (rats were given aquadest daily), positive control (rats were given lead acetate 30 mg/kg BW orally once a day for 60 days), and the treatment group (rats were given piperine...

the objective of this study was to evaluate the effect of dietary supplements with lead acetate and aluminosilicates (atn) on antioxidative enzyme activities and lipid peroxidation of the heart and skeletal muscle tissues of broiler chickens. broilers were allotted to four diets including the control group, the pb group, the aluminosilicate-atn (antitoxic nutrient) group and the pb+atn group, i...

the mechanism by which lead may cause a perturbotion in the nevous system is through the nitric oxide synthase. in this study the effect of lead acetate on the hippocampal constitutive nitric oxide production was studied. the variation in the nitric oxide production may contribute to physiological lead neurotoxicity in vivo. different concentrations of lead acetate (10-9 to 10-6 m), wre added t...

Lead acetate (AcPb) is an important raw material used in chemical industries worldwide. The potential toxicity of AcPb generally attributed to the presence Pb. However, effect on environment as a whole still poorly known. This study aimed evaluate three standard species soil invertebrates and two plant using ecotoxicology tests. Three tropical soils (Oxisol, Inceptisol, Tropical Artificial Soil...

introduction: lead is one of the most important environmental pollutants due to its vast use in various industries. lead accumulation in different organs, especially the brain, liver and kidneys can cause serious health problems. lead exposure is more dangerous during fetal period and childhood. materials and methods: timed pregnant female rats divided into 6 groups. group 1served as control gr...

Lead is known to be a potent neurotoxin that can cause seizure activity in humans and animals. Also, epileptic type convulsion is a known complication of hypothyroidism. This study was performed to determine the effect of propylthiouracil (PTU)-induced hypothyroidism and chronic lead exposure on pentylenetetrazol (PTZ)-induced kindling parameters. The test was carried out by using male alb...

Background: Lead is a major environmental pollutant and can adversely affect humans and animals. There are conflicting data about the ototoxic effect of lead. This study experimentally examined the association between blood lead levels (BLL) and the subsequent hearing impairment in male rats. Methods: Twenty-two male rats were randomly categorized into experimental (exposed to lead acetate, ...