Obstructive sleep apnoea syndrome (OSAS) might be a cause of heart failure. The present study aimed to assess left ventricular mass and myocardial performance index (MPI) in OSAS patients. A total of 67 subjects without any cardiac or pulmonary disease, referred for evaluation of OSAS, had overnight polysomnography and echocardiography. According to apnoea-hypopnoea index (AHI), subjects were c...

Background: Anorexia nervosa is associated with lower left ventricular mass (LVM) and systolic dysfunction. Whether these abnormalities reflect chronic protein-energy malnutrition or are primarily related to lower cardiac workload is unclear. Objective: The objective of the study was to verify whether low LVM in anorexia nervosa is explained by low hemodynamic load. Design: Ninety-one women wit...

BACKGROUND.: In this study the effects of 24 weeks losartan and ramipril treatment, both alone and in combination, on blood pressure and left ventricular mass (LVM) and function, have been evaluated in hypertensives. METHODS.: 57 hypertensives with stage 1 and 2 essential hypertension were included. After 4 weeks run in, a randomized double-blind, 3 arm, double dummy, independent trial was use...

AIMS Previous genome-wide linkage analysis has suggested that chromosomal region 17p13.3 may harbour genes influencing left ventricular mass (LVM) in man. To date, the genetic factors accounting for LVM variability remain largely unknown but a non-coding RNA gene within this region, micro-RNA 22 (miR-22), has been implicated in cardiac hypertrophy and heart failure in animal models. We thus inv...

BACKGROUND The association between left ventricular hypertrophy, an independent predictor of cardiovascular (CV) morbidity and mortality, and CV risk factors has been well documented in childhood and in adulthood. However, information on the relationship between left ventricular mass (LVM) in adults and longitudinal measurements of CV risk factors from childhood to adulthood is limited. METHO...

BACKGROUND Blacks have a higher prevalence of left ventricular hypertrophy than whites. Several population-based studies have reported an inverse association between adiponectin and left ventricular mass (LVM); however, the relationship between adiponectin levels and LVM has yet to be defined in blacks. The Jackson Heart Study cohort provides an opportunity to test the hypothesis that the inver...

Background Although it is known that left ventricular hypertrophy (LVH) is a predictor of cardiovascular morbidity and mortality, there is no consensus on how LV mass (LVM) should be indexed, particularly in children. The well published difficulties with correctly indexing LVM hamper the confidence in determining the range of normal LVM in growing children. Left ventricular mass to volume ratio...

recognition of the natural history and responsible leading factors for regression of left ventricular hypertrophy after successful renal transplantation are very important. the aim of this study was to assess the regression of left ventricular hypertrophy after successful renal transplantation among uremic patients. in this study 27 uremic patients (18 males and 9 females) with an average age o...

BACKGROUND Anorexia nervosa is associated with lower left ventricular mass (LVM) and systolic dysfunction. Whether these abnormalities reflect chronic protein-energy malnutrition or are primarily related to lower cardiac workload is unclear. OBJECTIVE The objective of the study was to verify whether low LVM in anorexia nervosa is explained by low hemodynamic load. DESIGN Ninety-one women wi...