Dendrimers are members of a versatile, fourth new class of polymer architecture (i.e. dendritic polymers after traditional linear, crosslinked and branched types). Typically, dendrimers are used as well-defined scaffolding or nanocontainers to conjugate, complex or encapsulate therapeutic drugs or imaging moieties. As a delivery vector, the dendrimer conjugate linker or spacer chemistry plays a...

let g be a simple graph. the hosoya polynomial of g is ( , ) ,( , ) = { , } ( ) xd u v h g x  u v v gwhere d(u,v) denotes the distance between vertices u and v . the dendrimer nanostar is apart of a new group of macromolecules. in this paper we compute the hosoya polynomial foran infinite family of dendrimer nanostar. as a consequence we obtain the wiener index andthe hyper-wiener index of th...

The membrane disruption properties of high generation (G4 to G7) poly(amidoamine) (PAMAM) dendrimers are evaluated and compared to linear poly(lysine). The G6 and G7 dendrimers are unusually effective at inducing leaky fusion of anionic, large unilamellar vesicles, as determined by standard fluorescence assays for lipid mixing, leakage, and contents mixing. Both G7 dendrimer and poly(lysine) ar...

‎In this article we discuss examples of fractal $omega$-operads‎. ‎Thus we show that there is an $omega$-operadic approach to explain existence of‎ ‎the globular set of globular setsfootnote{Globular sets are also called $omega$-graphs by the French School.}‎, ‎the reflexive globular set of reflexive globular sets‎, ‎the $omega$-magma of $omega$-magmas‎, ‎and also the reflexive $omega$-magma ...

objective: dendrimers are three-dimensional nanostructures that have numerous applications in medicine, including drug delivery and imaging. although anionic dendrimer polyethylene glycol–citrate has a high potential to increase solubility of water-insoluble drugs and drug delivery, its multi-step synthesis procedure is time consuming. in addition, toxic substances such as dichloromethane are u...

Despite the great efforts in the areas of early diagnosis and treatment of cancer, this disease continues to grow and is still a global killer. Cancer treatment efficiency is relatively high in the early stages of the disease. Therefore, early diagnosis is a key factor in cancer treatment. Among the various diagnostic methods, molecular imaging is one of the fastest and safest ones. Because of ...

Due to their unique properties, Anticancer dendrimer-based drugs have been displaying promising results in both in vitro and in vivo in the treatment of cancerous cells, as compared to the traditional polymers. In this report, two conjugates (G1+Pt and G2+Pt) of cisplatin [cis-diaminedichloroplatinum; (CDDP)] with two generations (G1, G2) of a biocompatible anionic dendrimer were prepared in an...

Dendrimers and other three-dimensional molecular assemblies are attractive scaffolds for biological delivery agents and diagnostic probes due to their globular shape, modular structure, monodispersity, and plurality of functional end groups. To address this potential, a number of strategies and related dendritic architectures have been developed for delivery of bioactive molecules to desired ce...