intense the granular deposits, the slower and more persistent the course of the disease, whereas a diffuse pattern of pigmentation with an absence of globules or dots was associated with earlier resolution.9,10 In our patient we observed a mottled pattern formed by clusters of numerous brown dots and globules and, as predicted, the course clinical was slow and the condition persisted for a year...

OBJECTIVE To determine the prevalence of extracutaneous manifestations and autoimmunity in adult and pediatric patients with morphea. DESIGN A retrospective review of 245 patients with morphea. SETTING University of Texas Southwestern Medical Center-affiliated institutions. Patients Patients with clinical findings consistent with morphea. MAIN OUTCOME MEASURES Prevalence of concomitant au...

A 51-year-old female developed linear-like scleroderma in the left thigh following a linear wound caused by a car accident. 27 years later she also developed a typical diffuse cutaneous systemic sclerosis with extensive skin involvement and bibasilar pulmonary fibrosis. The second case is a 39-year-old female who had a history of Raynaud's phenomenon since early childhood. She developed a morph...

INTRODUCTION Scleroderma is an autoimmune disease that involves the connective tissue characterized by skin fibrosis, classified as localized and systemic (participation of one or more internal organs). The primary objective of this study is to describe and analyze the clinical and laboratory findings in a group of children diagnosed with scleroderma at a referral hospital. MATERIAL AND METHO...

Morphea represents a localized form of scleroderma where there is predominant skin involvement, with occasional involvement of subjacent muscles. However, it usually spares the internal organs [1]. Morphea has been associated with several autoimmune diseases like mixed connective tissue disease, dermatomyositis, pemphigus, myasthenia gravis, bullous pemphigoid, systemic sclerosis, Hashimoto’s t...

A 17 year old girl presented with asymptomatic linear depressed groove involving the midline of the forehead region which was progressively increasing over the past 1 year. The lesion was slowly extending to the scalp which became a major concern to the patient. There was no history of trauma preceding the development of the lesion. On examination, an ivory sclerotic depressed linear lesion mai...

BACKGROUND The etiology of morphea is still unknown. Borrelia spp. as a causative agent of morphea has been discussed since 1985, but the relationship remains uncertain. OBJECTIVES We aimed to find the frequency of Borrelia in morphea lesions by polymerase chain reaction (PCR) in northeast of Iran. PATIENTS AND METHODS Sixty six patients with morphea were prospectively included in the prese...

Morphea is an uncommon connective tissue disease with the most prominent feature being thickening or fibrosis of the dermal without internal organ involvement. It is also known as a part of localized scleroderma. Based on clinical presentation and depth of tissue involvement, morphea is classified into several forms, and about two thirds of adults with morphea have plaque type. Overproduction o...

1. Nayak K, Garg A, Mithra P, Manjrekar P. Serum Vitamin D3 levels and diffuse hair fall among the student population in South India: A case‐control study. Int J Trichology 2016;8:160‐4. 2. Vasudevan DM, Sreekumari S, Vaidyanathan K. Fat soluble vitamin. In: Textbook of Biochemistry for Medical Students. 6th ed. New Delhi: Jaypee Brother Medical Publishers Pvt Ltd.; 2011. p. 33. 3. Harinarayan ...