نتایج جستجو برای: linked lymphoproliferative disease

تعداد نتایج: 1683373  

Journal: :Hematology. American Society of Hematology. Education Program 2000
Timothy Greiner James O. Armitage Thomas G. Gross

This review addresses the clinical presentation, pathology, and therapy of several uncommon lymphoid proliferations. Because these lymphoproliferations span the characteristics of reactive polymorphous proliferations to clonal malignant neoplasms, they are often difficult to diagnose and treat effectively. In Section I, Dr. Greiner describes the pathology of the spectrum of atypical lymphoid di...

Journal: :Haematologica 2010
Elena Boggio Manuela Indelicato Elisabetta Orilieri Riccardo Mesturini Maria Clorinda Mazzarino Maria Francesca Campagnoli Ugo Ramenghi Umberto Dianzani Annalisa Chiocchetti

BACKGROUND Inherited defects decreasing function of the Fas death receptor cause autoimmune lymphoproliferative syndrome and its variant Dianzani's autoimmune lymphoproliferative disease. Analysis of the lymphocyte transcriptome from a patient with this latter condition detected striking over-expression of osteopontin and tissue inhibitor of metalloproteinases-1. Since previous work on osteopon...

Journal: :Archives of disease in childhood 1998
P D Arkwright G Makin A M Will M Ayres D A Gokhale W D Fergusson G M Taylor

X linked lymphoproliferative disease (XLP; Duncan's disease) is a rare disorder affecting boys and characterised by a defective immune response to Epstein-Barr virus caused by a mutation in a gene located at chromosome Xq25. Three siblings with XLP in a single UK family are reported and the variation in phenotypic expression of the disease in these siblings described. One of the siblings with l...

Journal: :iranian journal of allergy, asthma and immunology 0
xi yang department of pediatrics, graduate school of medicine and pharmaceutical sciences, university of toyama, toyama, japan and division of immunology, children’s hospital of chongqing medical university, chongqing, china. naonori nishida department of pediatrics, graduate school of medicine and pharmaceutical sciences, university of toyama, toyama, japan. xiaodong zhao division of immunology, children’s hospital of chongqing medical university, chongqing, china hirokazu kanegane department of pediatrics, graduate school of medicine and pharmaceutical sciences, university of toyama, toyama, japan and department of pediatrics and developmental biology, graduate school of medical and dental sciences, tokyo medical and dental university, tokyo, japan

epstein-barr virus (ebv) was discovered 50 years ago from an african burkitt lymphoma cell line. ebv-associated lymphoproliferative disorders (lpds) are life-threatening diseases, especially in children. in this article, we review ebv-associated lpds, especially in the area of primary immunodeficiency disease (pid). we searched pubmed for publications with key words including ebv infection, lym...

Journal: :Proceedings of the National Academy of Sciences 1987

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