نتایج جستجو برای: linker
تعداد نتایج: 11693 فیلتر نتایج به سال:
In Shaker K(+) channels depolarization displaces outwardly the positively charged residues of the S4 segment. The amount of this displacement is unknown, but large movements of the S4 segment should be constrained by the length and flexibility of the S3-S4 linker. To investigate the role of the S3-S4 linker in the ShakerH4Delta(6-46) (ShakerDelta) K(+) channel activation, we constructed S3-S4 l...
Post-translational histone modifications and linker histone incorporation regulate chromatin structure and genome activity. How these systems interface on a molecular level is unclear. Using biochemistry and NMR spectroscopy, we deduced mechanistic insights into the modification behavior of N-terminal histone H3 tails in different nucleosomal contexts. We find that linker histones generally inh...
We discuss a methodology to dynamically generate links among digital objects by means of an unsupervised learning mechanism which analyzes user link traversal patterns. We performed an experiment with a test bed of 150 complex data objects, referred to as buckets. Each bucket manages its own content, provides methods to interact with users and individually maintains a set of links to other buck...
In this work, we refer to the fraction of hydrides and vinyl groups consumed in cross-linking reaction as a variation properties poly(dimethylsiloxane) (PDMS) with varying formulation curing agent from 3.2 wt % 50 %. Young's modulus, density, refractive indices PDMS were observed have maxima at about 10 cross linker. The intensity Raman band for Si?H stretching mode cross-linker is almost zero ...
In eukaryotic cells, genomic DNA is primarily packaged into nucleosomes through sequential ordered binding of the core and linker histone proteins. The acidic proteins termed histone chaperones are known to bind to core histones to neutralize their positive charges, thereby facilitating their proper deposition onto DNA to assemble the core of nucleosomes. For linker histones, however, little ha...
gold is a new ELF linker recently added to the GNU binutils. I discuss why it made sense to write a new linker rather than extend the existing one. I describe the architecture of the linker, and new features. I present performance measurements. I discuss future plans for the linker. I discuss the use of C++ in writing system tools.
We study the effects of bifunctional linker on the optical properties of ZnO nanocolumn-linker-CdSe quantum dots heterostructure. The CdSe quantum dots are anchored on the surface of ZnO nanocolumns through either aliphatic linker of 3-aminopropyl trimethoxysilane (APS) or aromatic linker of p-aminophenyl trimethoxysilane (APhS). X-ray photoelectron spectroscopy is used to confirm the bifunctio...
To elucidate the role of the histone tails in chromatin compaction and in higher-order folding of chromatin under physiological conditions, we extend a mesoscale model of chromatin (Arya, Zhang, and Schlick. Biophys. J. 2006, 91, 133; Arya and Schlick. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 16236) to account for divalent cations (Mg(2+)) and linker histones. Configurations of 24-nucleosome ol...
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