background: gastrointestinal and liver diseases (gild) constitute a noteworthy portion of causes of death and disability in iran. however, data on their prevalence and burden is sparse in iran. the global burden of disease (gbd) study in 2010 has provided invaluable comprehensive data on the burden of gild in iran methods: estimations of death, years of life lost due to premature death (yll), y...

materials and methods in this case-control study, using the polymerase chain reaction (pcr), adrs266729 and rs2241766 gene polymorphisms were genotyped in b-type ultrasonography-proven nafld patients, with (n = 246) or without (n = 247) cad and in healthy controls (n = 304). serum lipid profiles were determined using biochemical methods. statistical analyses were performed using spss 17.0 stati...

conclusions pain management in patients with liver dysfunction is always challenging to physicians because of the adverse reactions of drugs, especially opioids. opioids should be used cautiously since they can cause sedation, constipation and sudden encephalopathy effects. since the clearance of these drugs in patients with hepatic insufficiency is decreased, the initial dose must be decreased...

introduction: chronic liver diseases consist of wide spectrum disorders that may be complicated by cirrhosis and therefore need to transplantation. the pediatric end-stage liver disease (peld) score and model of end-stage liver disease (meld) score has been used as predictors of mortality chronic liver diseases listed for liver transplantation. the aim of this study is evaluation of relation be...

non-alcoholic fatty liver disease (nafld) is the leading cause of chronic liver disease in the united states and other industrialized countries, and the reported prevalence in the developing countries is also rather high. this disease is associated with a high rate of morbidity and mortality and damage to the other organs. the cardiovascular system is, perhaps, the most vulnerable organ to nafl...

conclusions this intervention offers a practical approach for treatment of patients with nafld with diet therapy. patients and methods forty four patients with nafld received a diet including a 500 to 1000 kcal per day intake reduction as30% fat, 15% protein, and 55% carbohydrate for six months. anthropometric parameters, alanine aminotransferase (alt), aspartate aminotransferase (ast), gamma g...

background: we aimed to determine the frequency of liver copper storage diseases in iranian children with cryptogenic chronic liver disease (cld). materials and methods: one-hundred and twenty children (52 girls, 70 boys; age range: 3 months-14 years) with cld who attended children's medical center in tehran, iran during the years 1997 through 1999, were enrolled. all viral, metabolic and autoi...

results abnormal liver function test was detected in cf patients. as well, liver sonogram was abnormal in approximately one-third of the patients. this study showed a higher prevalence of biochemical abnormality in patients with abnormal livers ultrasonography. conclusions noninvasive paraclinical evaluation methods could be recommended in the patients with cf for early detection of silent live...

chronic liver diseases in children is the result of many different diseases including: metabolic, genetic, infectious, toxic and idiopathic causes. this was a case series study on 133 infants and children with age range 6 month to 12 years old, who presented clinically with manifestation of chronic liver disease and were admitted to children hospital medical center from year 1999 to 2000. in th...

ramadan is a sacred month for muslims all around the world. during this lunar-based month, healthy adult muslims are obligated to abstain from eating, drinking, smoking, or using oral medications from predawn to sunset. followers will typically eat just after sunset and again before dawn (1). the islamic lunar hijri calendar is 11 days shorter than the gregorian solar calendar, and therefore, t...