background & aim:cadmium is an important industrial and environmental pollutant. cadmium is one of the most toxic and carcinogenic heavy metals to organisms. this heavy metal mainly distributes to the liver and kidney in humans and animal and, causing acute hepatic injury. experimental: the ethanol extract of satureja hortensis l. (lamiaceae family), was evaluated for its activity against c...

The present investigation was designed to identify potential biomarker(s) and assess the involvement of inflammatory pathway in dimethylnitrosamine (DMN)-induced liver fibrosis in rats. Following DMN-treatment (10 mg/ml/kg, i.p., given three consecutive days each week for 4 weeks) body and liver weights were significantly decreased concurrent with increasing severity of liver damage assessed by...

Pharmacognosy Research,2022,14,4,446-453.DOI:10.5530/pres.14.4.65Published:October 2022Type:Original ArticleAuthors:Sheeba Shakeel, and Nahida Tabassum Author(s) affiliations:Sheeba Tabassum* Department of Pharmaceutical Sciences, School Applied Sciences Technology, University Kashmir, Srinagar, INDIA. Abstract:Background: Diabetes mellitus is an increasingly serious health problem in society w...

OBJECTIVES To evaluate the efficacy of microbubble contrast ultrasound in diagnosis of hepatocellular carcinoma and to compare its results with those of magnetic resonance and histopathology. METHODS A total of 29 patients suffering from chronic liver diseases and awaiting liver transplants at Hospital Israelita Albert Einstein were subject to magnetic resonance, microbubble contrast ultrasou...

non-alcoholic fatty liver disease (naflD) has emerged as a worldwide epidemic in the 21st century. the spectrum of its histopathology ranges from simple steatosis to steatohepatitis, with risk for progressive fibrosis that may lead to cirrhosis and hepatocellular carcinoma. this review is an update of the histopathology of naflD and its differential diagnosis, in particular alcoholic liver dise...

Histological analysis of liver biopsies remains a standard against which other methods of assessment for the presence and amount of hepatic injury due to nonalcoholic fatty liver disease (NAFLD) are measured. Histological evaluation remains the sole method of distinguishing steatosis from advanced forms of NAFLD, i.e. nonalcoholic steatohepatitis (NASH) and fibrosis. Included in the lesions of ...

The cytotoxic alloxan is the most prominent diabetogenic chemical agent in experimental diabetes research. Alloxan has been found to be selectively toxic to liver hepatocytes. The experiments aim to understand the effect of alloxan on cytomorphology of liver in rat. Treatment with alloxan caused central vein congestion with significant dilatation of sinusoidal spaces. The liver of the alloxan t...

Introduction: The study was conducted to understand the clinical algorithm of hepatocellular carcinoma (HCC). Correlation was done by clinical presentation with radiological features and histopathology of HCC. The stress on to understand the necessity for a team approach between clinician, radiologist, and pathologist and vice versa is emphasized. Aim: To correlate histopathology of HCC with th...