BACKGROUND In order to increase the number of renal donors, laparoscopic live-donor nephrectomy (LLDN) was first performed 8 years ago. Today, LLDN is a routine procedure in many centres worldwide. We reviewed the literature with regard to extend the use of this method, the feasibility and safety for donor, graft and recipient. Laparoscopic and open-donor nephrectomy are compared, and the impac...

background: in addition to human leukocyte antigens (hla) compatibility, gene polymorphisms in cytokines might also be important in the quality of allogeneic immune response. objective: to evaluate the influence of hla-dr matching and a number of cytokine gene polymorphisms on acute rejection after living-unrelated donor (lurd) kidney transplantation. methods: a total of 42 renal transplants pe...

background& objective:  the prevalence and annual incidence of end stage renal disease  among 60 million iranians is about 15000 and 3175 (53 patients per million), respectively. the first renal transplantation was performed in shiraz, iran in 1967. iran has the most successful renal transplant program in the middle east  region. the renal transplant activity of the country has reached 24 renal...

BACKGROUND ABO incompatible kidney transplantation (ABOi-KT) is an important approach for overcoming donor shortages. We evaluated the effect of ABOi-KT on living donor KT. METHODS Two nationwide transplantation databases were used. We evaluated the impact of ABOi-KT on overall living donor transplant activity and spousal donation as subgroup analysis. In addition, we compared the clinical ou...

BACKGROUND AND OBJECTIVES The aim of this retrospective study was to compare conventional laparoscopic living-donor nephrectomy with transvaginal natural orifice transluminal endoscopic surgery-assisted living-donor nephrectomy in terms of feasibility and reproducibility. METHODS A total of 115 consecutive female patients who underwent laparoscopic living-donor nephrectomy (n=70) or transvagi...

background: the presence of donor leukocytes in recipients of organ allograft has been shown even several years after transplantation. however, it remains unclear whether this donor cell microchimerism plays an effective role in allograft acceptance or is simply a consequence of immunosuppressive conditions in recipients. objective: to study microchimerism in a group of kidney transplant recipi...