The metabolism of 5-fluorouracil (FUra) was examined in two human lymphocyte cell lines, CCRF-CEM (T-leukemic) and LAZ-007 (Epstein-Barr virus-transformed B), which have widely differing FUra sensitivities. CEM cells have orotate phosphoribosyltransferase but no uridine or thymidine phosphorylase activity. Consistent with this, the FUra growth inhibition and the synthesis of fluorouridine triph...

A motion compensated de-interlacing method wirh adaptive global motion estimation and compensation is proposed to recover the defects of interlaced video sequence with camera panning, rotating or zooming. GME and GMC are used Io recover the change of the whole picture due to camera motions. Two local motion compensated de-interlacing methods are proposed and applied to de-interlace interlaced v...

This paper presents a new method for image zooming. The new method is different from the traditional polynomial interpolation technique. A bivariate rational interpolation is used in the new method. Using the bivariate rational interpolation is more effective than the polynomial interpolation for image zooming, especially in processing the borders of the source image. The bivariate rational int...

Studies investigating the predictors of growth in infants born to HIV-infected women in developing countries are limited. Using data from 886 Tanzanian HIV-infected women and their infants, we examined the impact of maternal socioeconomic and immunological status, infant characteristics at birth, and HIV, diarrhea and respiratory infections on infants' monthly length-for-age (LAZ) and length-fo...

PURPOSE To identify the gene responsible for a complex ocular phenotype of late-onset macular degeneration, long anterior zonules (LAZ), and elevated intraocular pressure (IOP) and to study its expression. METHODS Ocular examination, visual field, fluorescein angiography, and electrophysiology testing were performed. One affected individual was treated with vitamin A. DNA from 55 family membe...

Adults mongrel dogs, weighing from 18 to 24 kg, were used. The entire small bowel was procured and flushed with cold lactated Ringer's solution containing heparin through the superior mesenteric artery. The intestinal lumen was also irrigated with the same solution. After the graft was preserved in the cold lactated Ringer's ,olution for 24 hours, it was transplanted orthotopically into the ,;a...

OBJECTIVE To evaluate the association of tenofovir disoproxil fumarate (TDF) use during pregnancy with early growth parameters in HIV-exposed, uninfected (HEU) infants. DESIGN US-based prospective cohort study of HEU children to examine potential adverse effects of prenatal TDF exposure. METHODS We evaluated the association of maternal TDF use during pregnancy with small for gestational age...

Competent social organisms will read the social signals of their peers. In primates, the face has evolved to transmit the organism's internal emotional state. Adaptive action suggests that the brain of the receiver has co-evolved to efficiently decode expression signals. Here, we review and integrate the evidence for this hypothesis. With a computational approach, we co-examined facial expressi...