abstract: introduction: nitric oxide (no) is a retrograde messenger in hippocampal synaptic plasticity which involves in learning and memory processes. previous studies revealed that hippocampal pyramidal cells contain no synthase (nos) enzyme which produce no and could be a promising target to evaluate the role of no in brain cognitive functions. so in this study, using nos inhibitor (l-name),...

purpose: to compare the effects of short-tem and long-term systemic corticosteroids in the treatment of confirmed ocular toxoplasmosis. methods: this randomized comparative clinical trial was performed on 69 patients with confirmed active ocular toxoplasmosis with typical clinical manifestations. the subjects were randomly assigned to receive either 10 days (group a, 33 cases) or 4-6 weeks (gro...

the study of the relationship between memory and achievement motivation with gender and academic achievement of students of urmia medical sciences university     feizi pour h [1] *, farjah gh [2] , qaderneghad m [3]     received: 9 nov , 2011 accepted: 21 jan , 2012     abstract   background & aims : memory gives possibility to mental life of human including thoughts, perceptions, opinions, and...

It is widely believed that the brain processes information and stores memories by modifying and stabilizing synaptic connections between neurons. In experimental models of synaptic plasticity, such as long-term potentiation (LTP), the stabilization of changes in synaptic strength requires rapid de novo RNA and protein synthesis. Candidate genes, which could underlie activity-dependent plasticit...

Cortisol, the primary glucocorticoid (GC) in humans, influences neuronal excitability and plasticity by acting on mineralocorticoid and glucocorticoid receptors. Cellular studies demonstrated that elevated GC levels affect neuronal plasticity, for example through a reduction of hippocampal long-term potentiation (LTP). At the behavioural level, after treatment with GCs, numerous studies have re...

Long-term potentiation (LTP), a relatively long-lived increase in synaptic strength, remains the mot popular model for the cellular process that may underlie information storage within neural systems. The strongest arguments for a role of LTP in memory are theoretical and involve Hebb's Postulate, Marr's theory of hippocampal function, and neural network theory. Considering LTP research as a wh...

background: this study aims to investigate the patterns of bioaccumulation and depuration of copper in the selected kidney and liver of capoeta fusca. methods: the fish were collected between september and november 2010 from a qanat in birjand. they were exposed to two types treatments with copper (0.25 and 0.75 mg/l) for a period of 41 days. the fish under study were exposed to the above-menti...

objective: successful bonding of a dental implant to bone, which was referred to as osseointegration by branemark has been well documented. however, long-term prognosis of an implant depends on adequate maintenance and long-term care. an effective maintenance program is required to preserve the health of peri-implant tissues. several techniques have been suggested for this purpose but it is not...