Background. Cutis laxa (CL) is a rare disorder of elastic tissue characterized by loose, sagging skin with reduced elasticity, and resilience without resulting scarring. CL may be inherited as a dominant, recessive, or X-linked recessive disease, or acquired. The heritable forms of CL predominantly begin at birth, but it may be delayed until puberty or age of 30 years with extracutaneous manife...

A 60-year-old farmer came to the accident and emergency department complaining of traumatic amputation of distal part of right thumb. On examination, there was a circumferential wound located at the base of right thumbnail with injury to both neurovascular bundles and fracture of distal part of distal phalanx with the distal part hanging by volar skin only. The wound was irrigated and the dista...

Conventional loose-weave cotton operating garments were compared with clothing of a non-woven fabric to test their efficacy in reducing the dispersal of skin bacteria into theatre air. When men wore operating suits made of the non-woven fabric dispersal of skin bacteria was reduced by 72%. When all the operating-theatre staff wore suits and dresses of this fabric air bacterial counts during ope...

Epithelioma, arising on skin surfaces, other than the neighbourhood of mucous membrane, is of rather rare occurrence in England. But in Kashmir the commonest seat of epithelioraata is the skin of the thigh and the abdomen. The cause of this is not far to seek. During the severe winters and indeed for a great part of the year, every Kashmiri man, woman or child carries a portable charcoal brazie...

BACKGROUND Constriction of the sciatic nerve by loose ligation produces an inflammatory neuropathic injury. This represents an animal model for peripheral mononeuropathy. Oxygen-derived free radicals are suspected to play an important role in the pathogenesis of ischemia/reperfusion injury, leading to neurogenic inflammation. Hyperbaric oxygen (HBO) has been used anecdotally to treat clinically...

A 12-year-old boy with difficulty in wound healing and scars of unusual appearance was examined. Thin, shiny and protruding skin, characterizing pseudotumoral lesions, was observed on his knees and elbows. Loose joints and increased skin elasticity were also observed. Light microscopy showed rare collagen bundles and loosely dispersed collagen fibers. Irregularly distributed elastic tissue was ...

Culture technology have permitted the generation of an artificial skin using human neonatal stem cells. A major advantage of this model is that epithelial-mesenchymal interactions are maintained. We have studied some morphological aspects concerning tissue organisation and cell differentiation using immunohistochemistry and electron microscopy. The epidermal equivalent was composed by a stratif...

Anetoderma is an elastolytic skin process clinically characterized by circumscribed rounded areas of loose skin; and histologically, by loss of elastic dermal fi bers. Two forms are traditionally distinguished, primary and secondary. Th e latter refers to an abnormal repair mechanism of preexisting skin lesions, where acne and varicella are the most frequent causes. In contrast, in the primary ...

Cutis laxa (CL) is a heterogeneous group of disorders characterized by loose, redundant, inelastic or prematurely wrinkled skin (Berk et al., 2012; Uitto et al., 2013). Several inherited forms of CL have been identified (Urban and Davis, 2013), with 9 causative genes known to date (ALDH18A1, ATP6V0A2, ATP7A, EFEMP2/FBLN4, ELN, FBLN5, LTBP4, PYCR1, RIN2). A shared feature of all types of inherit...

In this paper energy method is used to calculate rotor response with loose rotating disk on it. System equation of motion is obtained based on energy method and Lagrange equation. Mathematical modeling of loose disk in a rotor bearing system has resulted in terms similar to unbalance and gyroscopic effect in the system equation of motion. The effect of loose disk axial position and orthotropic ...