Lubrication plays a key role in successful manufacturing of pharmaceutical solid dosage forms; lubricants are essential ingredients in robust formulations to achieve this. Although many failures in pharmaceutical manufacturing operations are caused by issues related to lubrication, in general, lubricants do not gain adequate attention in the development of pharmaceutical formulations. In this p...

Mechanical wear accounts for one third of present global energy consumption. However, it still lacks an efficient lubricant to simultaneously achieve a highly efficient lubrication and metal wear repair. Herein, we report that carbon quantum dots (CQDs)/CuSx nanocomposites show enhanced lubrication and metal wear surface repair abilities when used as additives. The highly efficient lubrication ...

We consider some basic principles of fluid-induced lubrication at soft interfaces. In particular, we quantify how a soft substrate changes the geometry of and the forces between surfaces sliding past each other. By considering the model problem of a symmetric nonconforming contact moving tangentially to a thin elastic layer, we determine the normal force in the small and large deflection limit,...

Anti friction bearings in process pumps, by design, frequently utilize oil sump lubrication technology. For many years, it was an accepted condition that the lubricating oil used in oil sump bearing lubrication needed to be changed on a regular basis to prevent high levels of contamination that can lead to premature bearing failure, contributing to equipment downtime. Often, the indicators used...

The relationship between a Lubrication Mode Diagram (LMD) for concentrated contacts (LCC‘s) and the ‘IRG transition’ diaLubrication Modes and the IRG Transition D i ag ram gram has been studied. In addition, scuffing results, obtained by the IRG (International Research Group) have been analysed, as well as the results of scuffing tests performed by different workers using a two-disc apparatus. ...

The lubrication effect of three long-chain polymers - mucin, methylcellulose and Ficoll - on ciliary propulsion in tubes is measured by plotting the relative velocities of swimming cilitates as a function of the tube bore diameter. Mucin shows the most unequivocal lubrication, which is found at concentrations between 0% and 9.1% (w/v). This observation, coupled with viscometric measurements whi...

Mice lacking Muc2 had an increased ratio of proliferating to apoptotic epithelial cells, resulting in altered maturation and increased migration of epithelial cells in the intestine. They were also more likely to develop intestinal, colon, and rectal tumors. The mice are the first good model for studying rectal tumors, which are common in humans. Anticancer lubrication new mouse model for the s...

BI-PHASIC BIOMATERIAL AND ARTICULAR CARTILAGE E.Northwood , R.Kowalski and J.Fisher * Institute of Medical and Biological Engineering, University of Leeds, Leeds, UK. +** DePuy CMW, Cornford Rd, Blackpool, England Email: [email protected] INTRODUCTION Natural articular cartilage has a unique biphasic lubrication regime [1]. Internal interstitial fluid pressure [2, 3] leads to low levels of fr...

The heat flow paradox provides evidence that a dynamic weakening mechanism may be important in understanding fault friction and rupture. We present here a specific model for dynamic velocity weakening that uses the mechanics of well-studied industrial bearings to explain fault zone processes. An elevated fluid pressure is generated in a thin film of viscous fluid that is sheared between nearly ...

Residual lubricants retained in the handpiece may be displaced onto the tooth surface. A few studies have examined the effect of contamination from handpiece lubrication oils on enamel and dentin bond strengths, but the results have been equivocal. 1,2 The purpose of this study was to evaluate the effect of dental-handpiece lubricant on dentinal shear bond strength. A lubrication-free handpiece...